Silver-Based Hybrid Nanomaterials: Preparations, Biological, Biomedical, and Environmental Applications

• Published in: Journal of cluster science Vol. 34; no. 1; pp. 23 - 43
• Main Authors: Venkatesan, Jayachandran, Gupta, Pramod K., Son, Seong Eun, Hur, Won, Seong, Gi Hun
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.01.2023; Springer Nature B.V
• Subjects: Bimetals; Biological activity; Biological properties; Biosensors; Catalysis; Chemistry; Chemistry and Materials Science; Commercialization; Copyright; Enzymes; Glucose; Glucose oxidase; Graphene; Hydrogen peroxide; Hypoxanthine; Inorganic Chemistry; Metal-organic frameworks; Nanochemistry; Nanocomposites; Nanomaterials; Nanoparticles; Organic chemistry; Particle size; Physical Chemistry; Pollutants; Quantum dots; Review Paper; Silver; Tissue engineering; Toxicity; Transition metals; Uric acid; Antimicrobial; Photothermal therapy; Silver; Nanozymes; Biosensor; Cancer therapy
• ISSN: 1040-7278; 1572-8862
• DOI: 10.1007/s10876-021-02212-3

Nanozymes, or artificial enzymes, have received a great deal of attention in recent years because of their superior enzyme-like capabilities over natural enzymes. The transition-metals are being investigated for their intrinsic nanozyme activity in various applications, including biosensors, antimicrobials, cytoprotection, anticancer, tissue engineering, and drug delivery. Especially, silver (Ag) is one of the transition-metals that has been investigated intensively since the turn of the century because of its biological activity and catalytic properties. This review discussed various Ag-based hybrid nanozymes preparation and their enzyme-like activity by combining Ag with other metals, salts, and organic molecules. Ag-based hybrid nanozymes in the form of metal–organic frameworks, complexes, bimetallic, hexacyanoferrate structures were summarized. Based on the literature results, Ag-based hybrid nanozymes are rapid, sensitive, and selective detection of various compounds, ions, and biological species such as hydrogen peroxide, glucose, phosphatase, glucose oxidase, acetylcholinesterase, cysteine, hepatitis E virus, sulfamethazine, uric acid, hypoxanthine, spermine, and gonadotropin. Moreover, Ag-based nanozymes are being investigated for antibacterial, cell protection, and anticancer applications. Future perspectives on Ag-based nanozymes were discussed at the end of the review. As a result, Ag-based hybrid nanozymes offer great potential for clinical trial applications and commercialization.