A Case Report of Resection of a Mediastinal Paraganglioma: Why All the Fuss?

Mediastinal paragangliomas are rare tumors that have only been reported in individual cases or limited case series. Surgical resection of these tumors can be challenging, as they are highly vascular and intimately related to the great vessels. Surgery is usually performed via median sternotomy with...

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Bibliographic Details
Published inJournal of chest surgery Vol. 55; no. 2; pp. 174 - 176
Main Authors Staunton, Laura Mary, Casey, Laura, Young, Vincent K, Fitzmaurice, Gerard J
Format Journal Article
LanguageEnglish
Published Korea (South) The Korean Society for Thoracic and Cardiovascular Surgery 05.04.2022
Korean Society for Thoracic & Cardiovascular Surgery
대한심장혈관흉부외과학회
Subjects
Case Report
lung neoplasm
mediastinal paraganglioma
posterolateral thoracotomy
sdhb mutation
흉부외과학
Posterolateral thoracotomy
Mediastinal paraganglioma
Case report
SDHB mutation
Lung neoplasm
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Summary:Mediastinal paragangliomas are rare tumors that have only been reported in individual cases or limited case series. Surgical resection of these tumors can be challenging, as they are highly vascular and intimately related to the great vessels. Surgery is usually performed via median sternotomy with or without cardiopulmonary bypass. We present the case of a mediastinal paraganglioma that was resected via a left-sided posterolateral thoracotomy. Histopathology revealed a completely resected 38-mm paraganglioma with a positive station 5 lymph node, indicative of locally aggressive disease. Hereditary paragangliomas are associated with malignant transformation; therefore, genetic testing is important. These tumors do not respond well to chemoradiotherapy, and consequently lifelong surveillance for early detection of recurrence is recommended.
ISSN:2765-1606
2765-1614
DOI:10.5090/jcs.21.115