Effect of Ethanol and Vinyl Chloride on the Induction of Liver Tumors: Preliminary Report

Preliminary results of a long-term animal study (rats) indicate synergism between inhaled vinyl chloride and ingested ethanol in tumorigenesis.

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Bibliographic Details
Published inEnvironmental health perspectives Vol. 21; pp. 153 - 155
Main Authors Radike, M. J., Stemmer, K. L., Brown, P. G., Larson, E., Bingham, E.
Format Journal Article
LanguageEnglish
Published United States National Institute of Environmental Health Sciences. National Institutes of Health. Department of Health, Education and Welfare 01.12.1977
Subjects
Alcohols
Animals
Autopsies
Chlorides
Conference on Comparative Metabolism and Toxicity of Vinyl Chloride Related Compounds, May 2-4, 1977: Conference Chairman Hans L. Falk
Drug Synergism
Environmental Exposure
Environmental health
Ethanol
Ethanol - toxicity
Hemangiosarcoma
Hemangiosarcoma - chemically induced
Inhalation
Liver
Liver Neoplasms - chemically induced
Male
Neoplasms, Experimental - chemically induced
Rats
Tumors
Vinyl Chloride - toxicity
Vinyl Compounds - toxicity
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Summary:Preliminary results of a long-term animal study (rats) indicate synergism between inhaled vinyl chloride and ingested ethanol in tumorigenesis.
ISSN:0091-6765
1552-9924
DOI:10.1289/ehp.7721153