Primary pineal rhabdomyosarcoma: A rare case
Primary pineal rhabdomyosarcoma (RMS) is extremely rare, and only three cases have been reported so far. Here, we report a case of 12-year-old male who presented with complaints of diplopia and diminution of vision since 15 days. He also had left-sided facial paresis. Magnetic resonance imaging brai...
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Published in | Asian journal of neurosurgery Vol. 14; no. 4; pp. 1291 - 1294 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
Thieme Medical and Scientific Publishers Pvt. Ltd
01.12.2019
Wolters Kluwer India Pvt. Ltd Wolters Kluwer - Medknow |
Subjects | |
Online Access | Get full text |
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Summary: | Primary pineal rhabdomyosarcoma (RMS) is extremely rare, and only three cases have been reported so far. Here, we report a case of 12-year-old male who presented with complaints of diplopia and diminution of vision since 15 days. He also had left-sided facial paresis. Magnetic resonance imaging brain revealed a space-occupying lesion in the region of pineal gland. The patient underwent midline suboccipital craniectomy with excision of tumor. Microscopic examination revealed a highly cellular tumor with areas showing small round cells admixed with cells having abundant eosinophilic cytoplasm resembling rhabdomyoblasts and multinucleated giant cells. Differential diagnoses of pineal anlage tumor and primary RMS were considered. The tumor cells were positive for desmin while being negative for synaptophysin and glial fibrillary acidic protein. Myogenin was used to confirm the diagnosis of RMS, which showed focal nuclear positivity. INI1 was retained. All the markers for germ cell tumors were negative. |
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ISSN: | 1793-5482 2248-9614 |
DOI: | 10.4103/ajns.AJNS_53_19 |