A gastrointestinal stromal tumor of the third portion of the duodenum treated by wedge resection: A case report

• Published in: World journal of gastrointestinal surgery Vol. 5; no. 12; pp. 332 - 336
• Main Authors: Acar, Fahrettin, Sahin, Mustafa, Ugras, Serdar, Calisir, Akın
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Co., Limited 27.12.2013
• Subjects: Case Report; Duodenum; Gastrointestinal; resection; stromal; Surgery; tumor; Wedge; Duodenum; Wedge resection; Surgery; Gastrointestinal stromal tumor
• ISSN: 1948-9366; 1948-9366
• DOI: 10.4240/wjgs.v5.i12.332

A 65-year old woman was admitted to our hospital with abdominal pain. Computed tomography showed a tumor measuring about 3 cm in diameter with no metastatic lesion or signs of local infiltration. Gastroduodenal endoscopy revealed the presence of a submucosal tumor in the third portion of the duodenum and biopsy revealed tumor cells stained positive for c-kit. These findings were consistent with gastrointestinal stromal tumors(GISTs) and we performed a wedge resection of the duodenum, sparing the pancreas. The postoperative course was uneventful and she was discharged on day 6. Surgical margins were negative. Histology revealed a GIST with a diameter of 3.2 cm and < 5 mitoses/50 high power fields, indicating a low risk of malignancy. Therefore, adjuvant therapy with imatinib was not initiated. Wedge resection with primary closure is a surgical procedure that can be used to treat low malignant potential neoplasms of the duodenum and avoid extensive surgery, with significant morbidity and possible mortality, such as pancreatoduodenectomy.