Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma : a phase I/II study
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| Published in | Journal of molecular medicine (Berlin, Germany) Vol. 77; no. 4; pp. 393 - 398 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Conference Proceeding Journal Article |
| Language | English |
| Published |
Berlin
Springer
01.04.1999
|
| Subjects | |
| Online Access | Get full text |
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| Author | SALMONS, B SCHUH, M KRÖGER, J.-C VON ROMBS, K HOFFMEYER, A GELBMANN, W JESNOWSKI, R RENZ, R HAUENSTEIN, K CEIJNA, M LIEBE, S MÜLLER, P WAGNER, T SCHWENDENWEIN, I GÜNZBURG, W. H HENNINGER, W SALLER, R LÖHR, M WALTER, I HAIN, J BERGMEISTER, H KARLE, P PROBST, A LOSERT, U BAGO, Z. T PÜSCHEL, K KUNDT, G RENNER, M FREUND, M |
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| Keywords | Adenocarcinoma Human Ifosfamide Cytochrome P450 Malignant tumor Injection Oxazaphosphinane derivatives Treatment Transfection Nitrogen mustard Phase II trial Phase I trial Digestive diseases Advanced stage Microencapsulation Intraarterial administration Pancreas Gene therapy Cell Pancreatic disease |
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| SubjectTerms | Adult Aged Biological and medical sciences Biotechnology Cell Line Cytochrome P-450 CYP2B1 - administration & dosage Cytochrome P-450 CYP2B1 - genetics Drug Compounding Female Fundamental and applied biological sciences. Psychology Gene therapy Genetic Therapy Genetic Vectors Health. Pharmaceutical industry Humans Ifosfamide - administration & dosage Ifosfamide - pharmacology Industrial applications and implications. Economical aspects Male Middle Aged Pancreatic Neoplasms - therapy Transfection |
| Title | Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma : a phase I/II study |
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