Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma : a phase I/II study

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Bibliographic Details
Published inJournal of molecular medicine (Berlin, Germany) Vol. 77; no. 4; pp. 393 - 398
Main Authors HAUENSTEIN, K, KRÖGER, J.-C, VON ROMBS, K, WAGNER, T, BERGMEISTER, H, CEIJNA, M, LOSERT, U, SCHWENDENWEIN, I, GELBMANN, W, GÜNZBURG, W. H, KARLE, P, BAGO, Z. T, HAIN, J, HENNINGER, W, PROBST, A, WALTER, I, SCHUH, M, KUNDT, G, LÖHR, M, FREUND, M, JESNOWSKI, R, LIEBE, S, HOFFMEYER, A, MÜLLER, P, PÜSCHEL, K, RENNER, M, RENZ, R, SALLER, R, SALMONS, B
Format Conference Proceeding Journal Article
LanguageEnglish
Published Berlin Springer 01.04.1999
Subjects
Adult
Aged
Biological and medical sciences
Biotechnology
Cell Line
Cytochrome P-450 CYP2B1 - administration & dosage
Cytochrome P-450 CYP2B1 - genetics
Drug Compounding
Female
Fundamental and applied biological sciences. Psychology
Gene therapy
Genetic Therapy
Genetic Vectors
Health. Pharmaceutical industry
Humans
Ifosfamide - administration & dosage
Ifosfamide - pharmacology
Industrial applications and implications. Economical aspects
Male
Middle Aged
Pancreatic Neoplasms - therapy
Transfection
Adenocarcinoma
Human
Ifosfamide
Cytochrome P450
Malignant tumor
Injection
Oxazaphosphinane derivatives
Treatment
Transfection
Nitrogen mustard
Phase II trial
Phase I trial
Digestive diseases
Advanced stage
Microencapsulation
Intraarterial administration
Pancreas
Gene therapy
Cell
Pancreatic disease
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Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0946-2716
1432-1440
DOI:10.1007/s001090050366