The influence of somatostatin on drug-induced prolactin release in the monkey

The infusion of linear somatostatin did not block prolactin release induced by either perphenazine, TRH or serotonin. Somatostatin infusion, however, potentiated prolactin release induced by perphenazine and TRH but not that induced by serotonin.

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Bibliographic Details
Published inExperientia Vol. 32; no. 7; p. 941
Main Authors Gala, R R, Subramanian, M G, Peters, J A, Jaques, Jr, S
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1976
Subjects
Animals
Drug Synergism
Female
Haplorhini
Macaca fascicularis
Macaca mulatta
Perphenazine - pharmacology
Prolactin - metabolism
Serotonin - pharmacology
Somatostatin - pharmacology
Thyrotropin-Releasing Hormone - pharmacology
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Summary:The infusion of linear somatostatin did not block prolactin release induced by either perphenazine, TRH or serotonin. Somatostatin infusion, however, potentiated prolactin release induced by perphenazine and TRH but not that induced by serotonin.
ISSN:0014-4754
DOI:10.1007/BF02003782