Generation of an induced pluripotent stem cell lines HMSCASTi001-A from peripheral blood mononuclear cells of a 35-year-old healthy male

Peripheral blood mononuclear cells derived from a 35-year-old healthy male were reprogrammed into induced pluripotent stem cells (iPSCs). The iPSCs maintained a normal karyotype, expressed various pluripotency stem cell markers, and showed potential of differentiating into three germ layers. This iP...

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Published inStem cell research Vol. 64; p. 102908
Main Authors Zhang, Zhanchi, Liu, Jingrui, Zhang, Jiamin, Xian, Xian, Hao, Peipei, Zhai, Yingtong, Cheng, Jingke, Yue, Fengming, Luan, Feng, Ma, Min, Ren, Qian
Format Journal Article
LanguageEnglish
Published Elsevier 01.10.2022
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Summary:Peripheral blood mononuclear cells derived from a 35-year-old healthy male were reprogrammed into induced pluripotent stem cells (iPSCs). The iPSCs maintained a normal karyotype, expressed various pluripotency stem cell markers, and showed potential of differentiating into three germ layers. This iPSCs could be differentiated into multiple cell subtypes for drug discovery and investigation of mechanisms.
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ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2022.102908