Subcutaneous lymphoid hyperplasia arising at site of ethnic scarifications and mimicking subcutaneous panniculitis-like T-cell lymphoma

• Published in: Virchows Archiv : an international journal of pathology Vol. 438; no. 3; pp. 298 - 301
• Main Authors: DARGENT, J. L, DIEDHIOU, A, LOTHAIRE, P, DEMUNTER, A, LESPAGNARD, L, DE WOLF-PEETERS, C
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.03.2001
• Subjects: Adult; Biological and medical sciences; Cicatrix; Dermatology; Humans; Hyperplasia; Immunophenotyping; Lymphoma, T-Cell, Cutaneous - immunology; Lymphoma, T-Cell, Cutaneous - pathology; Male; Medical sciences; Skin - pathology; Tumors of the skin and soft tissue. Premalignant lesions; Benin; Africa; Human; Immunohistochemistry; Skin disease; Ethnic origin; Scarification; Radiodiagnosis; Benign lymphoid hyperplasia; Subcutaneous; Panniculitis; Male; Malignant hemopathy; Non Hodgkin lymphoma; Differential diagnostic; Case study; Pathology; Lymphoproliferative syndrome; T-Lymphocyte; Medical imagery; Adult; Computerized axial tomography; Molecular biology
• ISSN: 0945-6317; 1432-2307
• DOI: 10.1007/s004280000320

The case of a 40-year-old black man, who developed a very unusual tumour-like lymphoid hyperplasia involving primarily the subcutaneous tissue, is reported. The lesion, which arose at a site of tribal scarifications, displayed a deceptive morphology that closely resembled subcutaneous panniculitis-like T-cell lymphoma (SPTCL). An accurate diagnosis could only be made following detailed immunohistochemical and molecular studies. Although SPTCL has been thought to represent a very specific clinicopathologic entity, the present case illustrates that its histological appearance can, however, be closely mimicked by reactive and benign conditions.