The localization of an imaginary target under the influence of caloric vestibular stimulation in healthy adults

• Published in: European archives of oto-rhino-laryngology Vol. 257; no. 9; pp. 473 - 479
• Main Authors: Schmäl, F., Kunz, R., Stoll, W.
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.11.2000
• Subjects: Adult; Biological and medical sciences; Caloric Tests; Electronystagmography; Humans; Imagination - physiology; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Mental Recall - physiology; Orientation - physiology; Otorhinolaryngology functional investigation (larynx, voice, audiometry, vestibular function, equilibration...); Psychomotor Performance - physiology; Reflex, Vestibulo-Ocular - physiology; Sensory Deprivation - physiology; Vestibule, Labyrinth - physiology; Darkness; Caloric vestibular test; Volunteer; ENT; Electrodiagnosis; Target; Adult; Armature; Behavior; Vestibular system; Oculomotor syndrome; Human; Amplitude; Head position; Statistical analysis; Healthy subject; Stimulus localization; Error; Exploration; Horizontal axis; Right-handed; Electronystagmography; Imaginary target; Eye disease; Nystagmus; Vestibuloocular reflex; Frequency; Deviation
• ISSN: 0937-4477; 1434-4726
• DOI: 10.1007/s004050000269

It is well known that fixation of an imaginary target (IT) can influence the vestibulo-ocular reflex, but reports on the effect of peripheral vestibular stimulation on the localization of an IT are still lacking. In a prospective study, errors in pointing towards an IT without and after cold caloric vestibular stimulation (VS) were investigated in 24 right-handed volunteers with the head tilted backwards by 60 degrees. After the stationary target had been extinguished for 120 s each subject had to point towards the target position as remembered in darkness. The vestibular response was recorded by electronystagmography. Without VS 73% of the volunteers showed a systematic horizontal pointing error towards the right side. VS led to an increased horizontal pointing error in the direction of the slow phase of the induced nystagmus and the degree of deviation showed a significant (P = 0.001) positive correlation (r = 0.32) with the amplitude of the calorically induced nystagmus. In summary, an IT is not merely a useful visual stimulus for influencing the vestibulo-ocular reflex during linear and angular acceleration. A peripheral vestibular stimulation is itself able to change the position of an IT significantly and the extent of deviation shows a significant correlation with the amplitude of the evoked nystagmus.