Electrochemical sensor based on a nanocomposite prepared from TmPO4 and graphene oxide for simultaneous voltammetric detection of ascorbic acid, dopamine and uric acid

• Published in: Mikrochimica acta (1966) Vol. 186; no. 3; p. 189
• Main Authors: Huang, Haiping, Yue, Yafeng, Chen, Zhongzhen, Chen, Yanan, Wu, Shuzhen, Liao, Jinsheng, Liu, Suijun, Wen, He-rui
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.03.2019
• Subjects: Analytical Chemistry; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Microengineering; Nanochemistry; Nanotechnology; Original Paper; Cyclic voltammetry; Hydrothermal method; Rare earth; Modified electrode; Differential pulse voltammetry; Electrochemical oxidation
• ISSN: 0026-3672; 1436-5073
• DOI: 10.1007/s00604-019-3299-7

A nanocomposite is described that consists of TmPO 4 and graphene oxide (GO) and is used to modify a glassy carbon electrode (GCE) to obtain a sensor for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA). GO and TmPO 4 were synthesized via the Hummers method and by a hydrothermal method, respectively. The nanocomposite was characterized by transmission electron microscopy, energy dispersive X-ray spectroscopy, powder X-ray diffraction and Fourier transform infrared spectroscopy. The electrochemical properties of the modified GCE were studied by electrochemical impedance spectroscopy and cyclic voltammetry. The good performance of the modified GCE results from the synergistic effects between GO with its good electrical conductivity and of TmPO 4 as the electron mediator that accelerates the electron transfer rate. Compared to a bare GCE, a GO/GCE and a TmPO 4 /GCE, the GO/TmPO 4 /GCE exhibits three well-defined and separated oxidation peaks (at −0.05, +0.13 and + 0.26 V vs. SCE). Responses to AA, DA and UA are linear in the 0.1–1.0 mM, 2–20 μM and 10–100 μM concentration ranges, respectively. Graphical abstract Schematic presentation of a nanocomposite that consists TmPO 4 and graphene oxide (GO) and is used to modify a glassy carbon electrode (GCE) to obtain a sensor for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA).