Contrast-enhanced MR angiography in patients after kidney transplantation

• Published in: European radiology Vol. 11; no. 12; pp. 2488 - 2495
• Main Authors: Huber, A, Heuck, A, Scheidler, J, Holzknecht, N, Baur, A, Stangl, M, Theodorakis, J, Illner, W D, Land, W, Reiser, M
• Format: Journal Article
• Language: English
• Published: Germany Springer Nature B.V 01.01.2001
• Subjects: Adult; Angiography, Digital Subtraction; Arterial Occlusive Diseases - diagnosis; Blood pressure; Catheters; Contrast agents; Coronary vessels; Female; Humans; Hypertension; Iliac Artery - pathology; Image Enhancement; Imaging, Three-Dimensional; Kidney Transplantation; Kidney transplants; Magnetic Resonance Angiography; Male; Medical imaging; Middle Aged; Observer Variation; Patients; Postoperative Complications - diagnosis; Renal Artery - pathology; Renal Artery Obstruction - diagnosis; Sensitivity and Specificity; Veins & arteries; Germany
• ISSN: 0938-7994; 1432-1084
• DOI: 10.1007/s003300100992

The aim of this study was to investigate the value of a contrast-enhanced 3D MR angiography in detecting postoperative vascular complications after kidney transplantation in comparison with digital subtraction angiography (DSA). Forty-one patients who underwent a kidney transplantation were examined with MR angiography and DSA. Contrast-enhanced MR angiography was performed as a dynamic measurement with one precontrast and three postcontrast measurements. Maximum intensity projection reconstructions were performed for all postcontrast data sets after DSA. The results were evaluated by two independent observers who were unaware of the DSA results. Twenty-three hemodynamically significant arterial stenoses were identified with DSA in the iliac arteries ( n=7), the renal allograft arteries ( n=12), and in their first branches ( n=4). For a patient-based analysis the sensitivity and specificity, respectively, for observer 1 were 100 and 97%, and for observer 2, 100 and 93%. Respective data were 100 and 100% after a consensus evaluation by two observers. Complications involving the renal veins were detected in 2 cases and perfusion defects of the kidney parenchyma were detected in 4 cases. Contrast-enhanced MR angiography is a reliable method in identifying postoperative arterial stenoses after kidney transplantation. In addition, dynamic MR angiography can be helpful in detecting venous complications and perfusion defects in kidney allografts.