Bone marrow cytomorphological changes in patients co-infected with visceral leishmaniasis and human immunodeficiency virus

• Published in: Revista brasileira de hematologia e hemoterapia Vol. 33; no. 6; p. 484
• Main Authors: Castro, Alana Jocelina Montenegro de, Gonçalves, Romelia Pinheiro, Pitombeira, Maria Helena da Silva
• Format: Journal Article
• Language: English; Portuguese
• Published: Associação Brasileira de Hematologia e Hemoterapia 01.12.2011; Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular; Elsevier
• Subjects: AIDS-related opportunistic infections; Bone marrow examination; HEMATOLOGY; HIV infections; Images in Clinical Hematology; Leishmaniasis, visceral; MEDICINE, RESEARCH & EXPERIMENTAL; Leishmaniasis, visceral; HIV infections; AIDS-related opportunistic infections; Bone marrow examination
• ISSN: 1516-8484; 1806-0870; 1806-0870
• DOI: 10.5581/1516-8484.20110129

Visceral leishmaniasis (VL) is a severe systemic infectious disease. ( 1 ) It has been recognized as an opportunistic disease in patients infected with human immunodeficiency virus (HIV). ( 2 , 3 ) The analysis of the bone marrow of patients co-infected with VL and HIV showed dysplasia of erythroid, granulocytic and megakaryocytic lineages ( Figure 1 ), besides the presence of plasmacytosis, cytoplasmic bodies, hemophagocytosis, granuloma and intracellular and extracellular leishmania amastigotes ( Figure 2 ). These findings are found in the analysis of bone marrow of patients co-infected with HIV and VL; knowledge of these findings may be useful for the diagnosis and prognosis of patients.