Disseminated histoplasmosis with conjunctival involvement in an immunocompromised patient

We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule...

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Published inIndian Journal of Sexually Transmitted Diseases and AIDS Vol. 31; no. 1; p. 35
Main Authors Shirali, Arun, Kini, Jyoti, Vupputuri, Anjith, Kuruvila, Maria, Prabhu, M Venkatraya
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.01.2010
Medknow Publications & Media Pvt. Ltd
Subjects
Acquired immune deficiency syndrome
AIDS
AIDS patients
Amphotericin B
Care and treatment
Case studies
Diagnosis
Dosage and administration
Health aspects
Histoplasmosis
HIV
Human immunodeficiency virus
Respiratory system
Risk factors
India
conjunctival histoplasmosis
disseminated histoplasmosis
Acquired immunodeficiency syndrome
India
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Summary:We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule showed numerous intracellular Periodic Acid Schiff-positive rounded yeast cells within macrophages. Bone marrow aspirate confirmed disseminated histoplasmosis. The patient showed dramatic response after starting treatment with Amphotercin B.
ISSN:2589-0557
1998-3816
2589-0565
DOI:10.4103/0253-7184.68999