On the Specificity of Nanozymes: A Perspective

Comprehensive Summary We have compiled eight promising strategies for enhancing the specificity and selectivity of nanozymes, as depicted in the comprehensive summary above. Enzymes exhibit intricate and sophisticated structures, including substrate channels and active sites, which can inform the de...

Full description

Saved in:
Bibliographic Details
Published inChinese journal of chemistry Vol. 42; no. 13; pp. 1515 - 1522
Main Authors Wei, Gen, Liu, Shujie, Peng, Yung‐Kang, Wei, Hui
Format Journal Article
LanguageEnglish
Published Weinheim WILEY‐VCH Verlag GmbH & Co. KGaA 01.07.2024
Wiley Subscription Services, Inc
Subjects
Catalytic activity
Enzymes
Imprinted polymers
Nanozymes
Perspective
Polymers
Sensor arrays
Specificity
Substrate specificity
Substrates
Online AccessGet full text

Cover

More Information
Summary:Comprehensive Summary We have compiled eight promising strategies for enhancing the specificity and selectivity of nanozymes, as depicted in the comprehensive summary above. Enzymes exhibit intricate and sophisticated structures, including substrate channels and active sites, which can inform the design of nanozymes. Replication of these structural features and the application of facet engineering/doping techniques can significantly enhance the catalytic specificity of nanozymes. Alternatively, the use of Molecularly Imprinted Polymers (MIPs) to coat nanozymes represents an effective approach to impart substrate specificity. Furthermore, several straightforward stopgap strategies have been devised to improve nanozyme specificity for analytical applications, such as the integration of biorecognition elements and nanozyme sensor arrays through surface modification. Key Scientists A comprehensive overview was conducted on the design strategies for nanozymes with intrinsic catalytic specificity. Additionally, supplemental strategies were summarized to achieve the selectivity of nanozymes for analytical applications.
Bibliography:These authors contributed equally to this work.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.202300755