Maternal Stroke: A Call for Action

Maternal mortality rates have been steadily increasing in the United States, and cardiovascular mortality is the leading cause of death among pregnant and postpartum women. Maternal stroke accounts for a significant burden of cardiovascular mortality. Data suggest that rates of maternal stroke have...

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Published inCirculation (New York, N.Y.) Vol. 143; no. 7; pp. 727 - 738
Main Authors Elgendy, Islam Y, Bukhari, Syed, Barakat, Amr F, Pepine, Carl J, Lindley, Kathryn J, Miller, Eliza C
Format Journal Article
LanguageEnglish
Published United States 16.02.2021
Subjects
Adolescent
Adult
Child
Female
Humans
Middle Aged
Risk Factors
Stroke - diagnosis
Stroke - epidemiology
Young Adult
postpartum period
subarachnoid hemorrhage
pregnancy
cerebral hemorrhage
hemorrhagic stroke
pre-eclampsia
ischemic stroke
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Summary:Maternal mortality rates have been steadily increasing in the United States, and cardiovascular mortality is the leading cause of death among pregnant and postpartum women. Maternal stroke accounts for a significant burden of cardiovascular mortality. Data suggest that rates of maternal stroke have been increasing in recent years. Advancing maternal age at the time of birth and the increasing prevalence of traditional cardiovascular risk factors, and other risk factors, as well, such as hypertensive disorders of pregnancy, migraine, and infections, may contribute to increased rates of maternal stroke. In this article, we provide an overview of the epidemiology of maternal stroke, explore mechanisms that may explain increasing rates of stroke among pregnant women, and identify key knowledge gaps for future investigation in this area.
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Both authors equally contributed to the manuscript
ISSN:0009-7322
1524-4539
DOI:10.1161/CIRCULATIONAHA.120.051460