Longitudinal study of neurotoxicity with occupational exposure to aluminum dust

Two cross-sectional studies were conducted at a German aluminum (Al) powder plant to evaluate possible nervous system effects from occupational Al exposure. The investigation included biological monitoring, a neuropsychological test battery, and event-related P300 potentials. Neurophysiologic findin...

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Bibliographic Details
Published inNeurology Vol. 54; no. 4; p. 997
Main Authors Letzel, S, Lang, C J, Schaller, K H, Angerer, J, Fuchs, S, Neundörfer, B, Lehnert, G
Format Journal Article
LanguageEnglish
Published United States 22.02.2000
Subjects
Adult
Aged
Aluminum - adverse effects
Dust - adverse effects
Female
Humans
Male
Middle Aged
Occupational Diseases - epidemiology
Occupational Exposure
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Summary:Two cross-sectional studies were conducted at a German aluminum (Al) powder plant to evaluate possible nervous system effects from occupational Al exposure. The investigation included biological monitoring, a neuropsychological test battery, and event-related P300 potentials. Neurophysiologic findings in workers chronically exposed to Al dust did not differ from non-Al-exposed controls from the same plant. The authors suggest that chronic exposure to Al dust, at the levels documented in this study, does not induce measurable cognitive decline.
ISSN:0028-3878
DOI:10.1212/WNL.54.4.997