Thymic lipofibroadenomas: Three case reports

Thymic lipofibroadenomas are extremely rare. In this study, we investigated the clinicopathological characteristics of thymic lipofibroadenomas. This study included three patients with thymic lipofibroadenomas. We retrospectively analyzed the patient data to determine the clinicopathological charact...

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Bibliographic Details
Published inWorld journal of clinical cases Vol. 11; no. 1; pp. 164 - 171
Main Authors Yang, Mai-Qing, Wang, Zhi-Qiang, Chen, Li-Qian, Gao, Su-Mei, Fu, Xing-Ning, Zhang, Hai-Ning, Zhang, Ke-Xin, Xu, Hong-Tao
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Inc 06.01.2023
Subjects
Case Report
Rare thymic tumor
Thoracic tumor
Lipofibroadenoma
Case report
Clinicopathological characteristics
Thymoma
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Summary:Thymic lipofibroadenomas are extremely rare. In this study, we investigated the clinicopathological characteristics of thymic lipofibroadenomas. This study included three patients with thymic lipofibroadenomas. We retrospectively analyzed the patient data to determine the clinicopathological characteristics of thymic lipofibroadenomas. The study included one man and two women [mean age, 43 (33-59) years]. All patients were non-smokers and presented with well-defined anterior mediastinal tumors. The cut surfaces of the tumors were solid, with a mixture of yellow and white areas. Microscopic evaluation of resected specimens showed scattered cord-like structures of epithelial cells embedded within abundant fibrotic and hyaline stroma admixed with variable quantities of adipose tissue. One patient showed hyperplastic thymic tissue in a part of the tumor. Thymic lipofibroadenomas are an extremely rare type of benign thymic tumor. Surgical removal of lipofibroadenomas is usually curative.
Bibliography:Author contributions: Xu HT and Yang MQ designed the study; Yang MQ, Wang ZQ, Chen LQ, Gao SM, Fu XN, Zhang HN, Zhang KX conducted the study; Xu HT and Yang MQ wrote the manuscript; All authors have read and approved the final manuscript.
Corresponding author: Hong-Tao Xu, MD, PhD, Professor, Department of Pathology, the First Hospital and College of Basic Medical Sciences of China Medical University, No. 155 Nanjingbei Street, Heping District, Shenyang 110001, Liaoning Province, China. xuht@cmu.edu.cn
Supported by the Natural Science Foundation of Liaoning province, No. 2020-MS-179.
ISSN:2307-8960
2307-8960
DOI:10.12998/wjcc.v11.i1.164