Application of a biphasic macroporous synthetic bone substitutes CERAFORM®: clinical and histological results
Missing bone is a challenging situation in orthopaedic surgery. Due to specific chemical and structural properties, biphasic ceramics are used as bone substitutes. We investigated intraoperative manoeuvrability, clinical tolerability, radiological and histological integration of a biphasic synthetic...
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Published in | European journal of orthopaedic surgery & traumatology Vol. 19; no. 6; pp. 387 - 395 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Paris
Springer-Verlag
01.08.2009
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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Summary: | Missing bone is a challenging situation in orthopaedic surgery. Due to specific chemical and structural properties, biphasic ceramics are used as bone substitutes. We investigated intraoperative manoeuvrability, clinical tolerability, radiological and histological integration of a biphasic synthetic ceramic (CERAFORM
®
). Present study reports 5-year follow-up of 43 cases requiring bone substitution: bone tumours; spinal fusions; revision arthroplasty; nonunions; fractures; osteitis. GESTO (Greffes ET Substitutes Tissulaires en Orthopedie) patient form was used for evaluation and follow up. Radiological survey was performed at 3, 6, 9, 12 and 18 months. We used CERAFORM
®
as single substitute or mixed with allo- or autograft. Clinical and radiological integration occurred 9–12 months after implantation. Bone biopsy documented new bone formation. CERAFORM allows good filling of the defect, additional autograft or osteosynthesis is needed for higher mechanical stability. Radiological aspect after implantation stands for a rapid integration in the host bone. Histological examination confirmed bone remodelling. |
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ISSN: | 1633-8065 1432-1068 |
DOI: | 10.1007/s00590-009-0445-7 |