Solubilization as a Method for Creating Hybrid Micellar Templates for the Synthesis of Multifunctional Mesoporous Containers

The solubilization of a water-insoluble biologically active compound, curcumin, in micelles of amphiphilic antimicrobial agents, such as miramistin, ethonium, and cetalkonium, is investigated, and the thermodynamic characteristics of this process are determined. It has been shown that the sol–gel sy...

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Bibliographic Details
Published inColloid journal of the Russian Academy of Sciences Vol. 81; no. 4; pp. 416 - 424
Main Authors Naumova, K. A., Dement’eva, O. V., Zaitseva, A. V., Rudoy, V. M.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.07.2019
Springer Nature B.V
Subjects
Chemistry
Chemistry and Materials Science
Containers
Micelles
Polymer Sciences
Silicon dioxide
Sol-gel processes
Solubilization
Surfaces and Interfaces
Synthesis
Thin Films
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Summary:The solubilization of a water-insoluble biologically active compound, curcumin, in micelles of amphiphilic antimicrobial agents, such as miramistin, ethonium, and cetalkonium, is investigated, and the thermodynamic characteristics of this process are determined. It has been shown that the sol–gel synthesis of multifunctional mesoporous silica containers can be realized using these surfactants’ micelles, which contain solubilized curcumin, as “hybrid” templates.
ISSN:1061-933X
1608-3067
DOI:10.1134/S1061933X19040094