Effects of Birth Season and Thymus Transplantation on Experimental Animal Longevity

— It is demonstrated in this study that a decrease in the rate of irreversible age-related thymus atrophy affects animal longevity. It was observed that the life span of rats may be increased by thymus transplantation from young animals into the immune privileged regions of ageing rats. It has been...

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Published inBiology bulletin of the Russian Academy of Sciences Vol. 46; no. 1; pp. 33 - 37
Main Authors Kulikov, A. V., Arkhipova, L. V., Kulikova, P. A., Glazkov, A. A., Mndlyan, E. Yu, Gavrilyuk, V. B., Kulikov, D. A.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 2019
Springer Nature B.V
Subjects
Aging
Atrophy
Biochemistry
Biomedical and Life Sciences
Birth
Cell Biology
Conference Materials
Ecology
Immune privilege
Life Sciences
Life span
Longevity
Rodents
Thymus
Transplantation
Zoology
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Summary:— It is demonstrated in this study that a decrease in the rate of irreversible age-related thymus atrophy affects animal longevity. It was observed that the life span of rats may be increased by thymus transplantation from young animals into the immune privileged regions of ageing rats. It has been shown that the season of birth has effects on animal longevity, namely, rats born in the spring–summer period live shorter lives than those born in autumn or winter.
ISSN:1062-3590
1608-3059
DOI:10.1134/S1062359019010047