Problems of Epidemiological Evidence

Problems associated with the use of epidemiological evidence to evaluate the carcinogenicity of heavy metals to humans are discussed. One of the greatest difficulties is to obtain a population for study that is large enough to distinguish the effects of a specific hazard from the effects of the rand...

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Bibliographic Details
Published inEnvironmental health perspectives Vol. 40; pp. 11 - 20
Main Authors Doll, Richard, Fishbein, Lawrence, Infante, Peter, Landrigan, Philip, Lloy, JWilliam, Maso, Thomas J, Mastromatteo, Ernest
Format Journal Article
LanguageEnglish
Published National Institute of Environmental Health Sciences. National Institutes of Health. Department of Health, Education and Welfare 01.08.1981
Subjects
Arsenic
Beryllium
Cadmium
Cancer
Carcinogenicity
Chromium
Cobalt
Lung neoplasms
Mortality
Nickel
Workshop/Conference on the Role of Metals in Carcinogenesis. Atlanta, Georgia, March 24-28, 1980
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Summary:Problems associated with the use of epidemiological evidence to evaluate the carcinogenicity of heavy metals to humans are discussed. One of the greatest difficulties is to obtain a population for study that is large enough to distinguish the effects of a specific hazard from the effects of the random variation of small numbers. The adequacy of the measure of risk and the possible existence of confounding factors are also cited as problems in this area.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0091-6765
1552-9924
DOI:10.2307/3429216