Synthesis of N-vinylpyrrolidone copolymers with 2-aminoethyl methacrylate as drug carriers
Radical copolymerization of N -vinylpyrrolidone and 2-aminoethyl methacrylate hydrochloride has been studied. Molecular and hydrodynamic characteristics of the resulting copolymers have been determined, and their structure has been confirmed. Conditions favoring conversion of these copolymers into c...
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Published in | Russian journal of general chemistry Vol. 87; no. 2; pp. 276 - 281 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Moscow
Pleiades Publishing
01.02.2017
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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Summary: | Radical copolymerization of
N
-vinylpyrrolidone and 2-aminoethyl methacrylate hydrochloride has been studied. Molecular and hydrodynamic characteristics of the resulting copolymers have been determined, and their structure has been confirmed. Conditions favoring conversion of these copolymers into copolymers of
N
-vinylpyrrolidone with 2-aminoethyl methacrylate of different composition have been elucidated. The suitability of the prepared copolymers as polymeric carriers of monofluoroquinolone ofloxacin has been demonstrated. |
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ISSN: | 1070-3632 1608-3350 |
DOI: | 10.1134/S1070363217020207 |