Influence of the external noise intensity on the kinetics of ligands binding to receptors

The average, variance, correlation function and the spectral density of ligand–receptor complexes in the presence of the external Langevin noise are calculated and their characteristics are defined. The analysis of the experimental data using the formulas derived in this work enables one to obtain a...

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Bibliographic Details
Published inJournal of contemporary physics Vol. 52; no. 1; pp. 70 - 75
Main Authors Arakelyan, V. B., Danko, V. P., Grigoryan, R. P.
Format Journal Article
LanguageEnglish
Published New York Allerton Press 2017
Springer Nature B.V
Subjects
Coordination compounds
Ligands
Noise intensity
Particle and Nuclear Physics
Physics
Physics and Astronomy
Receptors
external noise
variance
ligand–receptor complex
correlation function
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Summary:The average, variance, correlation function and the spectral density of ligand–receptor complexes in the presence of the external Langevin noise are calculated and their characteristics are defined. The analysis of the experimental data using the formulas derived in this work enables one to obtain a new information on the process of forming of ligand–receptor complex, namely, the constants rates of formation and the decay of the ligand–receptor complex.
ISSN:1068-3372
1934-9378
DOI:10.3103/S106833721701011X