Vimentin a potential biomarker for therapeutic efficiency of HAART

Human immunodeficiency virus （HIV） is recognized to be one of the most destructive pandemics in recorded history. By 2011, approximately 34 million people had been infected globally. There were 2.5 million new HIV infections just in 2011 alone according to the Joint United Nations Programme on HIV/A...

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Published inActa biochimica et biophysica Sinica Vol. 46; no. 11; pp. 1001 - 1006
Main Authors Jia, Xiaofang, Liu, Li, Liu, Xiaoqian, Wu, Dage, Yin, Lin, Liu, Xiaohui, Zhang, Jiaoli, Yang, Pengyuan, Lu, Hongzhou, Zhang, Lijun
Format Journal Article
LanguageEnglish
Published China 01.11.2014
Subjects
Adult
AIDS
Amino Acid Sequence
Antiretroviral Therapy, Highly Active
Biomarkers - blood
Female
HIV
HIV Infections - blood
HIV Infections - drug therapy
HIV Infections - virology
Humans
Male
Middle Aged
Peptide Fragments - blood
Peptide Fragments - genetics
Proteomics
Tandem Mass Spectrometry
Treatment Outcome
Vimentin - blood
Vimentin - genetics
Viral Load
Young Adult
人类免疫缺陷病毒
波形
生物标志物
疗效
艾滋病毒
逆转录病毒
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Summary:Human immunodeficiency virus （HIV） is recognized to be one of the most destructive pandemics in recorded history. By 2011, approximately 34 million people had been infected globally. There were 2.5 million new HIV infections just in 2011 alone according to the Joint United Nations Programme on HIV/AIDS （UNAIDS）Report （2012）. With the use of highly active antiretroviral therapy （HAART）, the replication of HIV virus and the progression of HIV disease can be suppressed. However, during the life-long treatment of AIDS, HIV resistance and adverse drug reactions have become serious problems.
Bibliography:31-1940/Q
Human immunodeficiency virus （HIV） is recognized to be one of the most destructive pandemics in recorded history. By 2011, approximately 34 million people had been infected globally. There were 2.5 million new HIV infections just in 2011 alone according to the Joint United Nations Programme on HIV/AIDS （UNAIDS）Report （2012）. With the use of highly active antiretroviral therapy （HAART）, the replication of HIV virus and the progression of HIV disease can be suppressed. However, during the life-long treatment of AIDS, HIV resistance and adverse drug reactions have become serious problems.
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SourceType-Scholarly Journals-1
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ISSN:1672-9145
1745-7270
DOI:10.1093/abbs/gmu075