A Comparison of the Several Methods for Determination of Specific IgE Antibodies

The accurary of measurement using kits in the clinical laboratories is important for the patient diagnosis and treatment. In the present paper, the AL-18, AIaSTAT, CAP, FAST and RAST methods were investigated and were compared among kits the results obtained with serum sample, for determination of s...

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Bibliographic Details
Published inRADIOISOTOPES Vol. 39; no. 10; pp. 449 - 452
Main Authors YOSHIMOTO, Akio, YAZAKI, Mitsuyoshi, SUGAYA, Takao
Format Journal Article
LanguageJapanese
English
Published Japan Japan Radioisotope Association 1990
Subjects
allergen
Antibody Specificity
Humans
Immunoglobulin E - analysis
Japan
Laboratories - standards
Reagent Kits, Diagnostic - standards
reference serum
specific immunogloburin E antibody
Japan
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Summary:The accurary of measurement using kits in the clinical laboratories is important for the patient diagnosis and treatment. In the present paper, the AL-18, AIaSTAT, CAP, FAST and RAST methods were investigated and were compared among kits the results obtained with serum sample, for determination of specific IgE antibodies. Significant differences among kits were observed from the results of those methods. One of the reasons, why the data discrepancy exists, is that each kit uses a different reference and a different inclusion method of allergen. For the evaluation of data discrepancy among those kits, it might be important that the clinical history of symptoms and in vivo tests against the different allergens compared with results of in vivo tests.
ISSN:0033-8303
1884-4111
DOI:10.3769/radioisotopes.39.10_449