Tracheobronchial abnormalities on computed tomography angiography in children with congenital heart disease

• Published in: Pediatric pulmonology Vol. 59; no. 5; pp. 1438 - 1448
• Main Authors: Bhatia, Harsimran, Bhatia, Anmol, Mathew, Joseph L., Saxena, Akshay K., Kumar, Praveen, Nallasamy, Karthi, Tao, Ting, Sodhi, Kushaljit S.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.05.2024
• Subjects: abnormalities; airway; Bronchi - abnormalities; Bronchi - diagnostic imaging; Cardiovascular disease; Child; Child, Preschool; children; Computed Tomography Angiography; Congenital diseases; congenital heart disease; CT angiography; Female; Heart Defects, Congenital - complications; Heart Defects, Congenital - diagnostic imaging; Humans; Infant; Infant, Newborn; Male; Medical imaging; Retrospective Studies; Tomography; Trachea - abnormalities; Trachea - diagnostic imaging; CT angiography; congenital heart disease; children; abnormalities; airway
• ISSN: 8755-6863; 1099-0496
• DOI: 10.1002/ppul.26934

Objectives To evaluate the assortment of tracheobronchial abnormalities on computed tomography angiography (CTA) in children with congenital heart disease (CHD). Methods In this study approved by the Institute ethics committee, CTA studies of 182 children (age range: 2 days–8 years) with CHD, performed from July 2021 to March 2023 were analyzed. Two pediatric radiologists independently assessed the tracheobronchial airways (from the trachea to lobar bronchi) for developmental and branching anomalies and airway compromise (narrowing). In cases which demonstrated airway compromise, the extent and the cause of airway narrowing were evaluated, and the etiology were divided into extrinsic and intrinsic causes. Interobserver agreement between the two radiologists was calculated using kappa statistics. Results One hundred children demonstrated normal airway anatomy and no luminal narrowing. Airway narrowing was observed in 63 (34.6%) children (κ: 0.954), and developmental airway anomalies were seen in 32 (17.5%) children (κ: 0.935). Of the 63 children with airway narrowing, 47 (25.8%) children had extrinsic cause for narrowing, 11 (6%) children had intrinsic causes for narrowing, and 5 (2.7%) children had both intrinsic and extrinsic causes attributing to airway compromise. Significant airway narrowing (>50% reduction) was seen in 35 (19.2%) children (κ: 0.945). Conclusion Tracheobronchial airway abnormalities are frequently associated in children with CHD and need to be appraised preoperatively. Cross‐sectional imaging with CTA provides excellent information on tracheobronchial airway anatomy and caliber as well as delineates the possible etiology of airway narrowing, thus accurately diagnosing airway anomalies.