LA-TT-EALR / PromCERA: Comparison of preoperatively performed electrically evoked auditory potentials at the brainstem and cortical level during local anesthesia

• Published in: Current directions in biomedical engineering Vol. 8; no. 2; pp. 233 - 236
• Main Authors: Polterauer, Daniel, Mandruzzato, Giacomo, Neuling, Maike, Polak, Marek, Müller, Joachim, Hempel, John-Martin
• Format: Journal Article
• Language: English
• Published: De Gruyter 02.09.2022
• Subjects: auditory nerve; cochlear implant; Cortical Evoked Potentials; electrical auditory brainstem response; Electrical Auditory Late Response; electrical stimulation; promontory stimulation; trans-tympanic
• ISSN: 2364-5504; 2364-5504
• DOI: 10.1515/cdbme-2022-1060

Introduction: In the past years, some groups established methods to use promontory stimulation and subjective responses as a tool for preoperative stimulation of the cochlea before cochlear implant (CI) surgery by a temporary transtympanic needle placed on the middle ear. Our research group tested CI candidates when the presence of the auditory nerve could not be confirmed by other pre-operative tests and analyzed objective results of electrical auditory brainstem response recorded with trans-tympanic promontory stimulation in local anesthesia (LA-TT-EABR) with a “golfclub” electrode placed on the round window niche (Polterauer et al. 2018). However, EABR recording suffers from an electrical artifact from the stimulation and focuses on the excitability of the solely auditory nerve. We hypothesize that late evoked potential response (EALR) can be used for the assessment of the auditory pathway up to the cortical area with less electrical artifact interference. Methods: The trans-tympanic electrically evoked auditory late response in local anesthesia (LA-TT-EALR) was added to our protocol right after the LA-TT-EABR in a unique recording session. In this study, we investigated the feasibility of LA-TT-EALR using MED-EL hardware and software. These two pre-operative trans-tympanic measurements, LATT- EABR and LA-TT-EALR, were compared. Results: In a total n=18 tested subjects, it could be possible to record LA-TT-EABR in 10 and LA-TT-EALR in 13. In contrast to the fact that acoustically evoked auditory late responses are often hard to detect, and an electrical artifact heavily affects LA-TT-EABR, we did not experience these problems on LA-TT-EALR recordings. The matching between two measurements was present in 67% of the cases. Conclusion: LA-TT-EALR may be a complement to the existing state-of-the-art LA-TT-EABR for pre-operative assessment before cochlear implantation offering information about auditory pathways in the auditory brainstem and cortex with a small increase of recording time. The equivalency of these two methods is encouraging.