Rhodium-catalyzed triazole-directed C-H bond functionalization of arenes with diazo compounds

• Published in: Organic & biomolecular chemistry Vol. 16; no. 43; pp. 8191 - 8195
• Main Authors: Wang, Huanhong, Yi, Xiaofei, Cui, Yanli, Chen, Wanzhi
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 07.11.2018; Royal Society of Chemistry
• Subjects: Alkylating agents; Alkylation; Aromatic compounds; Catalysis; Chemical reactions; Chemistry; Chemistry, Organic; Crystallography; Data processing; Heterocyclic compounds; Hydrogen bonds; Materials science; Organic chemistry; Physical Sciences; Rhodium; Science & Technology; ACTIVATION; AZIDES; OLEFINATION; ANNULATION; 1,2,3-TRIAZOLES; 1,3-DIPOLAR CYCLOADDITION; REGIOSELECTIVE SYNTHESIS; NITROOLEFINS; ALKYNES; CYCLIZATION

Heterocyclic compounds bearing 1,2,3-triazole scaffolds have found wide application both in medicinal chemistry and materials science. In this paper, rhodium(iii)-catalyzed triazole-directed alkylation reactions of arenes using diazo compounds as the alkylating agents are described. A number of poly...