Recent applications of intramolecular Diels-Alder reaction in total synthesis of natural products
Diels-Alder (D-A) reaction is undoubtedly the most powerful [4 + 2] cycloaddition reaction in organic synthesis. It has been always considered as a model and a symbol of cycloaddition reactions. Intramolecular D-A reactions (IMDA) are also well recognized and can be employed in one or more steps for...
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| Published in | RSC advances Vol. 5; no. 63; pp. 589 - 5912 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
01.01.2015
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| Online Access | Get full text |
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| Summary: | Diels-Alder (D-A) reaction is undoubtedly the most powerful [4 + 2] cycloaddition reaction in organic synthesis. It has been always considered as a model and a symbol of cycloaddition reactions. Intramolecular D-A reactions (IMDA) are also well recognized and can be employed in one or more steps for the total synthesis of several natural products. In this report, we wish to highlight the recent applications of IMDA as a key step in the total synthesis of biologically active natural products, including alkaloids and terpenes.
Diels-Alder (D-A) reaction is undoubtedly the most powerful [4 + 2] cycloaddition reaction in organic synthesis. |
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| Bibliography: | Vaezeh Fathi Vavsari was born in 1983 in Sari, Iran. She received her B.Sc. degree in Applied Chemistry from Ferdowsi University of Mashhad, Iran (2009) and her MSc. degree in Organic Chemistry at Khaje Nasir Toosi University of Technology, Tehran, Iran (2013) under the supervision of Dr. Saeed Balalaie. She is currently working towards her PhD. in Organic chemistry at Alzahra University under the supervision of Dr. Ghodsi Mohammadi Ziarani. Her research field is organic synthesis by the use of amino acids in the presence of nanostructure silica as catalysts. Majid M. Heravi was born in 1952 in Mashhad, Iran. He received his B.Sc. degree from the National University of Iran in 1975 and his M.Sc. and Ph.D. degrees from Salford University, England, in 1977 and 1980. He completed his doctoral thesis under the supervision of the late Jim Clarck at Salford University. He started his career as a research fellow in Daroupakksh (a pharmaceutical company) in 1981 Tehran, Iran and joined as an assistant professor in Ferdowsi University of Mashhad Iran. In 1999 he moved to Alzahra University Tehran, Iran as professor of chemistry, where he is still working. He has previously been a visiting professor at UC Riverside, California, USA and Hamburg University, Hamburg, Germany. His research interests focus on heterocyclic chemistry, catalysis and organic methodology. |
| ISSN: | 2046-2069 2046-2069 |
| DOI: | 10.1039/c5ra08306k |