Rhino-Orbital mucormycosis in an immunocompetent pediatric patient with hyperglycemia of the hospitalized patient

Acute invasive rhino-orbital mucormycosis usually affects diabetic or neutropenic patients, and only exceptionally develops in immunocompetent adults and children. A 12-years-old immunocompetent female, presented with complicated rhinosinusitis with a subperiosteal orbital abscess, without improveme...

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Published inJournal of infection in developing countries Vol. 15; no. 7; pp. 1035 - 1038
Main Authors Prado-Calleros, Héctor Manuel, Brito-Vera, Juan Pablo, Moreno-Coutiño, Gabriela, Andrade-Morelos, Lilian Elizabeth, Escobedo-Torres, Mónica Patricia, Vázquez-Zavala, Genoveva, Hernández-Castro, Rigoberto
Format Journal Article
LanguageEnglish
Published Italy Journal of Infection in Developing Countries 31.07.2021
Subjects
Abscess - complications
Abscess - diagnosis
Antifungal agents
Case reports
Child
Female
Fungal infections
Hospitalization
Humans
Hyperglycemia
Hyperglycemia - complications
Immunocompetence
Mucormycosis - complications
Mucormycosis - diagnosis
Orbital Diseases - complications
Orbital Diseases - diagnosis
Pediatrics
Rhinitis
Rhinitis - complications
Rhinitis - diagnosis
Rhizopus oryzae - genetics
Rhizopus oryzae - isolation & purification
Sinusitis
Sinusitis - complications
Sinusitis - diagnosis
rhinosinusitis
immunocompetent
mucormycosis
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Summary:Acute invasive rhino-orbital mucormycosis usually affects diabetic or neutropenic patients, and only exceptionally develops in immunocompetent adults and children. A 12-years-old immunocompetent female, presented with complicated rhinosinusitis with a subperiosteal orbital abscess, without improvement after initial medical and surgical management, the patient also developed hyperglycemia of the hospitalized patient that represented a challenging and potentially lethal clinical scenario. Diagnosed with an unsuspected rhino-orbital mucormycosis by direct microscopy and PCR, she survived after amphotericin B and surgical treatment. In cases with torpid clinical evolution, even in apparently immunocompetent patients, appropriate multidisciplinary workup must be performed to rule out opportunistic etiologies including mucormycosis to improve survival.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ISSN:1972-2680
2036-6590
1972-2680
DOI:10.3855/jidc.14299