Human RNA-binding protein HNRNPD interacts with and regulates the repair of deoxyribouridine in DNA

Deoxyribouridine (dU) is an abnormal nucleoside in DNA and plays vital roles in multiple biological and physiological processes. Here, we conducted a mass spectrometry-based screen for dU-binding proteins and found that the heterogeneous nuclear ribonucleoprotein D (HNRNPD) could preferentially bind...

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Published inInternational journal of biological macromolecules Vol. 262; no. Pt 1; p. 129951
Main Authors Wang, Ziyu, Qu, Minghui, Chang, Sijia, Dai, Xiaoxia, You, Changjun
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.03.2024
Subjects
DNA damage
DNA repair
Proteomics
DNA repair
DNA damage
Proteomics
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Abstract Deoxyribouridine (dU) is an abnormal nucleoside in DNA and plays vital roles in multiple biological and physiological processes. Here, we conducted a mass spectrometry-based screen for dU-binding proteins and found that the heterogeneous nuclear ribonucleoprotein D (HNRNPD) could preferentially bind to dU-containing DNA. We also discovered that HNRNPD engages in the 5-Fluorouracil (5FU)-induced DNA damage response and can modulate the repair of dU in DNA in vitro and in human cells. Moreover, using a shuttle vector- and next-generation sequencing-based method, we unveiled the crucial role of HNRNPD in promoting the replicative bypass of dU in human cells. Taken together, these findings suggested that HNRNPD is a novel dU-bearing DNA-binding protein capable of regulating the removal of dU in DNA, and provided new insights into the molecular mechanisms of dU-associated diseases. [Display omitted]
AbstractList Deoxyribouridine (dU) is an abnormal nucleoside in DNA and plays vital roles in multiple biological and physiological processes. Here, we conducted a mass spectrometry-based screen for dU-binding proteins and found that the heterogeneous nuclear ribonucleoprotein D (HNRNPD) could preferentially bind to dU-containing DNA. We also discovered that HNRNPD engages in the 5-Fluorouracil (5FU)-induced DNA damage response and can modulate the repair of dU in DNA in vitro and in human cells. Moreover, using a shuttle vector- and next-generation sequencing-based method, we unveiled the crucial role of HNRNPD in promoting the replicative bypass of dU in human cells. Taken together, these findings suggested that HNRNPD is a novel dU-bearing DNA-binding protein capable of regulating the removal of dU in DNA, and provided new insights into the molecular mechanisms of dU-associated diseases. [Display omitted]
Deoxyribouridine (dU) is an abnormal nucleoside in DNA and plays vital roles in multiple biological and physiological processes. Here, we conducted a mass spectrometry-based screen for dU-binding proteins and found that the heterogeneous nuclear ribonucleoprotein D (HNRNPD) could preferentially bind to dU-containing DNA. We also discovered that HNRNPD engages in the 5-Fluorouracil (5FU)-induced DNA damage response and can modulate the repair of dU in DNA in vitro and in human cells. Moreover, using a shuttle vector- and next-generation sequencing-based method, we unveiled the crucial role of HNRNPD in promoting the replicative bypass of dU in human cells. Taken together, these findings suggested that HNRNPD is a novel dU-bearing DNA-binding protein capable of regulating the removal of dU in DNA, and provided new insights into the molecular mechanisms of dU-associated diseases.
ArticleNumber 129951
Author Chang, Sijia
You, Changjun
Wang, Ziyu
Dai, Xiaoxia
Qu, Minghui
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Cites_doi 10.1016/j.aca.2021.338607
10.1016/j.dnarep.2014.03.030
10.1098/rstb.2008.0186
10.1038/s41388-022-02495-4
10.1016/j.biopha.2021.111285
10.1021/acs.jproteome.2c00854
10.1089/ars.2022.0105
10.3390/ijms23010096
10.1016/j.cclet.2021.05.057
10.1016/j.cell.2023.04.029
10.1002/wrna.1230
10.1093/nar/gkm1023
10.1016/j.cclet.2021.08.066
10.1016/j.dnarep.2013.05.002
10.1146/annurev.biochem.76.061705.090740
10.1021/bi012180a
10.1021/acscentsci.0c01504
10.1021/acschembio.2c00415
10.1038/s41589-018-0065-9
10.1186/1471-2199-9-94
10.1093/nar/gkz076
10.1038/sj.onc.1205996
10.1038/384087a0
10.1093/nar/25.4.750
10.3390/ijms22084212
10.1073/pnas.96.16.9045
10.3390/ijms21051706
10.1038/cdd.2014.79
10.1016/j.dnarep.2006.06.009
10.1073/pnas.1305624110
10.1146/annurev.immunol.26.021607.090248
10.1007/s00294-020-01086-8
10.1016/j.dnarep.2019.02.014
10.1146/annurev.ge.20.120186.001221
10.1074/mcp.M115.052167
10.1021/acs.accounts.5b00437
10.1021/bi00633a024
10.1021/acs.chemrev.6b00296
10.1016/j.cell.2013.08.021
10.1038/s41419-021-03432-1
10.1016/j.molcel.2012.06.035
10.1093/nar/gkt083
10.1093/nar/16.12.5645
10.1038/ng.2701
10.1007/s00018-008-8557-5
10.1038/nrc1074
10.1016/S1097-2765(02)00742-6
10.1074/mcp.M200025-MCP200
10.1038/s41467-020-19173-2
10.1016/j.freeradbiomed.2014.11.018
10.1016/j.cell.2017.01.002
10.1016/j.celrep.2019.10.108
10.1016/j.bbrc.2010.11.011
10.3390/ijms242316903
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Proteomics
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References Nilsen, Otterlei, Haug, Solum, Nagelhus, Skorpen, Krokan (bb0105) 1997; 25
Krokan, Drablos, Slupphaug (bb0025) 2002; 21
Yu, Ruan, Liu, Zhang, Wang, Liu, Yang, Shao, Liu, Zhu, Lin, Xue (bb0130) 2021; 12
Harris, Petersen-Mahrt, Neuberger (bb0020) 2002; 10
Malfatti, Codrich, Dalla, D’Ambrosio, Storici, Scaloni, Tell (bb0150) 2023; 39
Olinski, Slupphaug, Foksinski, Krokan (bb0215) 2021; 22
Siriwardena, Chen, Bhagwat (bb0045) 2016; 116
Tubbs, Nussenzweig (bb0005) 2017; 168
Hao, Gowder, Proshkin, Bharati, Epshtein, Svetlov, Shamovsky, Nudler (bb0260) 2023; 186
Sidali, Teotia, Solaiman, Bashir, Kanagaraj, Murphy, Surendranath (bb0140) 2021; 23
Cone, Duncan, Hamilton, Friedberg (bb0250) 1977; 16
Greagg, Fogg, Panayotou, Evans, Connolly, Pearl (bb0085) 1999; 96
Chon, Field, Stover (bb0060) 2019; 77
Wang, Zhang, Han, Yang, Chen, Wu, Liu, Weng, Zhou (bb0070) 2021; 7
Pan, Liu, Zheng, Zhou, You, Dai (bb0160) 2021; 32
Shu, Liu, Lu, Zhu, Meng, Huang, Zhang, Yi (bb0065) 2018; 14
Liu, Qu, Pan, Zheng, Sheng, Ji, You, Dai (bb0155) 2021; 1168
Zaccara, Tebaldi, Pederiva, Ciribilli, Bisio, Inga (bb0200) 2014; 21
Wyatt, Wilson (bb0195) 2009; 66
Cerritelli, El Hage (bb0275) 2020; 66
Wardle, Burgers, Cann, Darley, Heslop, Johansson, Lin, McGlynn, Sanvoisin, Stith, Connolly (bb0055) 2008; 36
Ran, Hsu, Lin, Gootenberg, Konermann, Trevino, Scott, Inoue, Matoba, Zhang, Zhang (bb0170) 2013; 154
Liu, Zhu, Wang, Dai, You (bb0185) 2022; 17
Galashevskaya, Sarno, Vagbo, Aas, Hagen, Slupphaug, Krokan (bb0015) 2013; 12
Prorok, Alili, Saint-Pierre, Gasparutto, Zharkov, Ishchenko, Tudek, Saparbaev (bb0220) 2013; 110
Alfano, Caporaso, Altieri, Dell'Aquila, Landi, Bini, Pentimalli, Giordano (bb0145) 2019; 47
Loeb, Preston (bb0210) 1986; 20
Ishii, Hayakawa, Sekiguchi, Adachi, Sekiguchi (bb0125) 2015; 79
Sparks, Chon, Cerritelli, Kunkel, Johansson, Crouch, Burgers (bb0265) 2012; 47
Rogstad, Liu, Burdzy, Lin, Sowers (bb0075) 2002; 41
Nava, Grasso, Sertic, Pellicioli, Muzi Falconi, Lazzaro (bb0245) 2020; 21
Stavnezer, Guikema, Schrader (bb0030) 2008; 26
Richardson, Gilroy, Ishino, Connolly, Henneke (bb0090) 2013; 41
Sethy, Kundu (bb0240) 2021; 137
Di Noia, Neuberger (bb0035) 2007; 76
Visnes, Doseth, Pettersen, Hagen, Sousa, Akbari, Otterlei, Kavli, Slupphaug, Krokan (bb0100) 2009; 364
You, Wang (bb0225) 2016; 49
Longley, Harkin, Johnston (bb0235) 2003; 3
Cui, Gizzi, Stivers (bb0080) 2019; 47
Dai, You, Wang (bb0175) 2016; 15
Lockhart, Pires, Bento, Kellner, Luke-Glaser, Yakoub, Ulrich, Luke (bb0270) 2019; 29
Hu, Zhang, Xing, Zhou, Chen, Li, Xu, Guo, Wang, He, Liu, Sheng, Song, Wu, Huang (bb0135) 2022; 41
Larson, Bednarski, Maizels (bb0110) 2008; 9
Hayakawa, Fujikane, Ito, Matsumoto, Nakayama, Sekiguchi (bb0120) 2010; 403
Moore, Chenette, Larkin, Schneider (bb0115) 2014; 5
Wang, Sheng, Yang, Dai, You (bb0180) 2022; 33
Cho, Ro, Yoon, Mizutani, Kang, Park, Il Kim, Clevers, Choi (bb0205) 2020; 11
Zheng, Chang, Liu, Dai, You (bb0165) 2023; 22
Nickoloff, Jaiswal, Sharma, Williamson, Tran, Arris, Yang, Hromas (bb0230) 2023; 24
Mosbaugh (bb0050) 1988; 16
Burns, Temiz, Harris (bb0040) 2013; 45
Wallace (bb0095) 2014; 19
Ong, Blagoev, Kratchmarova, Kristensen, Steen, Pandey, Mann (bb0190) 2002; 1
Slupphaug, Mol, Kavli, Arvai, Krokan, Tainer (bb0255) 1996; 384
Lari, Chen, Vertessy, Morre, Bennett (bb0010) 2006; 5
Moore (10.1016/j.ijbiomac.2024.129951_bb0115) 2014; 5
Alfano (10.1016/j.ijbiomac.2024.129951_bb0145) 2019; 47
Pan (10.1016/j.ijbiomac.2024.129951_bb0160) 2021; 32
Dai (10.1016/j.ijbiomac.2024.129951_bb0175) 2016; 15
Slupphaug (10.1016/j.ijbiomac.2024.129951_bb0255) 1996; 384
Longley (10.1016/j.ijbiomac.2024.129951_bb0235) 2003; 3
Tubbs (10.1016/j.ijbiomac.2024.129951_bb0005) 2017; 168
Richardson (10.1016/j.ijbiomac.2024.129951_bb0090) 2013; 41
Di Noia (10.1016/j.ijbiomac.2024.129951_bb0035) 2007; 76
Ishii (10.1016/j.ijbiomac.2024.129951_bb0125) 2015; 79
Wang (10.1016/j.ijbiomac.2024.129951_bb0070) 2021; 7
Nilsen (10.1016/j.ijbiomac.2024.129951_bb0105) 1997; 25
Siriwardena (10.1016/j.ijbiomac.2024.129951_bb0045) 2016; 116
Mosbaugh (10.1016/j.ijbiomac.2024.129951_bb0050) 1988; 16
Cone (10.1016/j.ijbiomac.2024.129951_bb0250) 1977; 16
Sparks (10.1016/j.ijbiomac.2024.129951_bb0265) 2012; 47
Sidali (10.1016/j.ijbiomac.2024.129951_bb0140) 2021; 23
Lari (10.1016/j.ijbiomac.2024.129951_bb0010) 2006; 5
Lockhart (10.1016/j.ijbiomac.2024.129951_bb0270) 2019; 29
Wallace (10.1016/j.ijbiomac.2024.129951_bb0095) 2014; 19
Greagg (10.1016/j.ijbiomac.2024.129951_bb0085) 1999; 96
Zheng (10.1016/j.ijbiomac.2024.129951_bb0165) 2023; 22
Malfatti (10.1016/j.ijbiomac.2024.129951_bb0150) 2023; 39
Ran (10.1016/j.ijbiomac.2024.129951_bb0170) 2013; 154
Stavnezer (10.1016/j.ijbiomac.2024.129951_bb0030) 2008; 26
Wardle (10.1016/j.ijbiomac.2024.129951_bb0055) 2008; 36
Sethy (10.1016/j.ijbiomac.2024.129951_bb0240) 2021; 137
Yu (10.1016/j.ijbiomac.2024.129951_bb0130) 2021; 12
Visnes (10.1016/j.ijbiomac.2024.129951_bb0100) 2009; 364
Hu (10.1016/j.ijbiomac.2024.129951_bb0135) 2022; 41
Cerritelli (10.1016/j.ijbiomac.2024.129951_bb0275) 2020; 66
Krokan (10.1016/j.ijbiomac.2024.129951_bb0025) 2002; 21
Cui (10.1016/j.ijbiomac.2024.129951_bb0080) 2019; 47
Burns (10.1016/j.ijbiomac.2024.129951_bb0040) 2013; 45
Nava (10.1016/j.ijbiomac.2024.129951_bb0245) 2020; 21
Liu (10.1016/j.ijbiomac.2024.129951_bb0155) 2021; 1168
Prorok (10.1016/j.ijbiomac.2024.129951_bb0220) 2013; 110
Wang (10.1016/j.ijbiomac.2024.129951_bb0180) 2022; 33
Harris (10.1016/j.ijbiomac.2024.129951_bb0020) 2002; 10
Cho (10.1016/j.ijbiomac.2024.129951_bb0205) 2020; 11
Galashevskaya (10.1016/j.ijbiomac.2024.129951_bb0015) 2013; 12
Larson (10.1016/j.ijbiomac.2024.129951_bb0110) 2008; 9
Wyatt (10.1016/j.ijbiomac.2024.129951_bb0195) 2009; 66
Nickoloff (10.1016/j.ijbiomac.2024.129951_bb0230) 2023; 24
Shu (10.1016/j.ijbiomac.2024.129951_bb0065) 2018; 14
Chon (10.1016/j.ijbiomac.2024.129951_bb0060) 2019; 77
Zaccara (10.1016/j.ijbiomac.2024.129951_bb0200) 2014; 21
Hayakawa (10.1016/j.ijbiomac.2024.129951_bb0120) 2010; 403
Loeb (10.1016/j.ijbiomac.2024.129951_bb0210) 1986; 20
Olinski (10.1016/j.ijbiomac.2024.129951_bb0215) 2021; 22
Ong (10.1016/j.ijbiomac.2024.129951_bb0190) 2002; 1
You (10.1016/j.ijbiomac.2024.129951_bb0225) 2016; 49
Hao (10.1016/j.ijbiomac.2024.129951_bb0260) 2023; 186
Rogstad (10.1016/j.ijbiomac.2024.129951_bb0075) 2002; 41
Liu (10.1016/j.ijbiomac.2024.129951_bb0185) 2022; 17
References_xml – volume: 17
  start-page: 2315
  year: 2022
  end-page: 2319
  ident: bb0185
  article-title: Next-generation sequencing-based analysis of the roles of DNA polymerases v and θ in the replicative bypass of 8-oxo-7,8-dihydroguanine in human cells
  publication-title: ACS Chem. Biol.
  contributor:
    fullname: You
– volume: 22
  start-page: 1339
  year: 2023
  end-page: 1346
  ident: bb0165
  article-title: Human mitochondrial protein HSPD1 binds to and regulates the repair of deoxyinosine in DNA
  publication-title: J. Proteome Res.
  contributor:
    fullname: You
– volume: 1
  start-page: 376
  year: 2002
  end-page: 386
  ident: bb0190
  article-title: Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
  publication-title: Mol. Cell. Proteomics
  contributor:
    fullname: Mann
– volume: 168
  start-page: 644
  year: 2017
  end-page: 656
  ident: bb0005
  article-title: Endogenous DNA damage as a source of genomic instability in cancer
  publication-title: Cell
  contributor:
    fullname: Nussenzweig
– volume: 10
  start-page: 1247
  year: 2002
  end-page: 1253
  ident: bb0020
  article-title: RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators
  publication-title: Mol. Cell
  contributor:
    fullname: Neuberger
– volume: 79
  start-page: 109
  year: 2015
  end-page: 116
  ident: bb0125
  article-title: Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells
  publication-title: Free Radical Bio. Med.
  contributor:
    fullname: Sekiguchi
– volume: 11
  start-page: 5321
  year: 2020
  ident: bb0205
  article-title: 5-FU promotes stemness of colorectal cancer via p53-mediated WNT/beta-catenin pathway activation
  publication-title: Nat. Commun.
  contributor:
    fullname: Choi
– volume: 5
  start-page: 549
  year: 2014
  end-page: 564
  ident: bb0115
  article-title: Physiological networks and disease functions of RNA-binding protein AUF1
  publication-title: Wiley Interdiscip. Rev. RNA
  contributor:
    fullname: Schneider
– volume: 21
  start-page: 1706
  year: 2020
  ident: bb0245
  article-title: One, no one, and one hundred thousand: the many forms of ribonucleotides in DNA
  publication-title: Int. J. Mol. Sci.
  contributor:
    fullname: Lazzaro
– volume: 45
  start-page: 977
  year: 2013
  end-page: 983
  ident: bb0040
  article-title: Evidence for APOBEC3B mutagenesis in multiple human cancers
  publication-title: Nat. Genet.
  contributor:
    fullname: Harris
– volume: 14
  start-page: 680
  year: 2018
  end-page: 687
  ident: bb0065
  article-title: Genome-wide mapping reveals that deoxyuridine is enriched in the human centromeric DNA
  publication-title: Nat. Chem. Biol.
  contributor:
    fullname: Yi
– volume: 384
  start-page: 87
  year: 1996
  end-page: 92
  ident: bb0255
  article-title: A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA
  publication-title: Nature
  contributor:
    fullname: Tainer
– volume: 76
  start-page: 1
  year: 2007
  end-page: 22
  ident: bb0035
  article-title: Molecular mechanisms of antibody somatic hypermutation
  publication-title: Annu. Rev. Biochem.
  contributor:
    fullname: Neuberger
– volume: 110
  start-page: 3695
  year: 2013
  end-page: 3703
  ident: bb0220
  article-title: Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Saparbaev
– volume: 3
  start-page: 330
  year: 2003
  end-page: 338
  ident: bb0235
  article-title: 5-fluorouracil: mechanisms of action and clinical strategies
  publication-title: Nat. Rev. Cancer
  contributor:
    fullname: Johnston
– volume: 66
  start-page: 1073
  year: 2020
  end-page: 1084
  ident: bb0275
  article-title: RNases H1 and H2: guardians of the stability of the nuclear genome when supply of dNTPs is limiting for DNA synthesis
  publication-title: Curr. Genet.
  contributor:
    fullname: El Hage
– volume: 12
  start-page: 153
  year: 2021
  ident: bb0130
  article-title: HNRNPD interacts with ZHX2 regulating the vasculogenic mimicry formation of glioma cells via linc00707/miR-651-3p/SP2 axis
  publication-title: Cell Death Dis.
  contributor:
    fullname: Xue
– volume: 96
  start-page: 9045
  year: 1999
  end-page: 9050
  ident: bb0085
  article-title: A read-ahead function in archaeal DNA polymerases detects promutagenic template-strand uracil
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Pearl
– volume: 116
  start-page: 12688
  year: 2016
  end-page: 12710
  ident: bb0045
  article-title: Functions and malfunctions of mammalian DNA-cytosine deaminases
  publication-title: Chem. Rev.
  contributor:
    fullname: Bhagwat
– volume: 32
  start-page: 3479
  year: 2021
  end-page: 3482
  ident: bb0160
  article-title: Comprehensive profiling of CTP-binding proteins using a biotinylated CTP affinity probe
  publication-title: Chin. Chem. Lett.
  contributor:
    fullname: Dai
– volume: 23
  start-page: 96
  year: 2021
  ident: bb0140
  article-title: AU-rich element RNA binding proteins: at the crossroads of post-transcriptional regulation and genome integrity
  publication-title: Int. J. Mol. Sci.
  contributor:
    fullname: Surendranath
– volume: 41
  start-page: 5298
  year: 2022
  end-page: 5314
  ident: bb0135
  article-title: The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer
  publication-title: Oncogene
  contributor:
    fullname: Huang
– volume: 41
  start-page: 8093
  year: 2002
  end-page: 8102
  ident: bb0075
  article-title: Endogenous DNA lesions can inhibit the binding of the AP-1 (c-Jun) transcription factor
  publication-title: Biochemistry-Us
  contributor:
    fullname: Sowers
– volume: 47
  start-page: 4068
  year: 2019
  end-page: 4085
  ident: bb0145
  article-title: Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Giordano
– volume: 33
  start-page: 2077
  year: 2022
  end-page: 2080
  ident: bb0180
  article-title: Next-generation sequencing-based analysis of the effect of
  publication-title: Chin. Chem. Lett.
  contributor:
    fullname: You
– volume: 41
  start-page: 4207
  year: 2013
  end-page: 4218
  ident: bb0090
  article-title: Novel inhibition of archaeal family-D DNA polymerase by uracil
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Henneke
– volume: 21
  start-page: 1522
  year: 2014
  end-page: 1534
  ident: bb0200
  article-title: p53-directed translational control can shape and expand the universe of p53 target genes
  publication-title: Cell Death Differ.
  contributor:
    fullname: Inga
– volume: 186
  start-page: 2425
  year: 2023
  end-page: 2437 e2421
  ident: bb0260
  article-title: RNA polymerase drives ribonucleotide excision DNA repair in
  publication-title: Cell
  contributor:
    fullname: Nudler
– volume: 47
  start-page: 4153
  year: 2019
  end-page: 4168
  ident: bb0080
  article-title: Deoxyuridine in DNA has an inhibitory and promutagenic effect on RNA transcription by diverse RNA polymerases
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Stivers
– volume: 39
  start-page: 411
  year: 2023
  end-page: 431
  ident: bb0150
  article-title: AUF1 recognizes 8-oxo-guanosine embedded in DNA and stimulates APE1 endoribonuclease activity
  publication-title: Antioxid. Redox Signal.
  contributor:
    fullname: Tell
– volume: 26
  start-page: 261
  year: 2008
  end-page: 292
  ident: bb0030
  article-title: Mechanism and regulation of class switch recombination
  publication-title: Annu. Rev. Immunol.
  contributor:
    fullname: Schrader
– volume: 9
  start-page: 94
  year: 2008
  ident: bb0110
  article-title: High-fidelity correction of genomic uracil by human mismatch repair activities
  publication-title: BMC Mol. Biol.
  contributor:
    fullname: Maizels
– volume: 16
  start-page: 3194
  year: 1977
  end-page: 3201
  ident: bb0250
  article-title: Partial purification and characterization of a uracil DNA N-glycosidase from
  publication-title: Biochemistry
  contributor:
    fullname: Friedberg
– volume: 12
  start-page: 699
  year: 2013
  end-page: 706
  ident: bb0015
  article-title: A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported
  publication-title: DNA Repair (Amst)
  contributor:
    fullname: Krokan
– volume: 19
  start-page: 14
  year: 2014
  end-page: 26
  ident: bb0095
  article-title: Base excision repair: a critical player in many games
  publication-title: DNA Repair (Amst)
  contributor:
    fullname: Wallace
– volume: 77
  start-page: 36
  year: 2019
  end-page: 44
  ident: bb0060
  article-title: Deoxyuracil in DNA and disease: genomic signal or managed situation?
  publication-title: DNA Repair (Amst)
  contributor:
    fullname: Stover
– volume: 7
  start-page: 973
  year: 2021
  end-page: 979
  ident: bb0070
  article-title: Base-resolution analysis of deoxyuridine at the genome scale based on the artificial incorporation modified nucleobase
  publication-title: ACS Cent. Sci.
  contributor:
    fullname: Zhou
– volume: 29
  start-page: 2890
  year: 2019
  end-page: 2900
  ident: bb0270
  article-title: RNase H1 and H2 are differentially regulated to process RNA-DNA hybrids
  publication-title: Cell Rep.
  contributor:
    fullname: Luke
– volume: 403
  start-page: 220
  year: 2010
  end-page: 224
  ident: bb0120
  article-title: Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress
  publication-title: Biochem. Bioph. Res. Co.
  contributor:
    fullname: Sekiguchi
– volume: 5
  start-page: 1407
  year: 2006
  end-page: 1420
  ident: bb0010
  article-title: Quantitative determination of uracil residues in
  publication-title: DNA Repair (Amst)
  contributor:
    fullname: Bennett
– volume: 137
  year: 2021
  ident: bb0240
  article-title: 5-fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: implication of DNA repair inhibition
  publication-title: Biomed. Pharmacother.
  contributor:
    fullname: Kundu
– volume: 20
  start-page: 201
  year: 1986
  end-page: 230
  ident: bb0210
  article-title: Mutagenesis by apurinic/apyrimidinic sites
  publication-title: Annu. Rev. Genet.
  contributor:
    fullname: Preston
– volume: 24
  start-page: 16903
  year: 2023
  ident: bb0230
  article-title: Cellular responses to widespread DNA replication stress
  publication-title: Int. J. Mol. Sci.
  contributor:
    fullname: Hromas
– volume: 36
  start-page: 705
  year: 2008
  end-page: 711
  ident: bb0055
  article-title: Uracil recognition by replicative DNA polymerases is limited to the archaea, not occurring with bacteria and eukarya
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Connolly
– volume: 364
  start-page: 563
  year: 2009
  end-page: 568
  ident: bb0100
  article-title: Uracil in DNA and its processing by different DNA glycosylases
  publication-title: Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci.
  contributor:
    fullname: Krokan
– volume: 16
  start-page: 5645
  year: 1988
  end-page: 5659
  ident: bb0050
  article-title: Purification and characterization of porcine liver DNA polymerase
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Mosbaugh
– volume: 49
  start-page: 205
  year: 2016
  end-page: 213
  ident: bb0225
  article-title: Mass spectrometry-based quantitative strategies for assessing the biological consequences and repair of DNA adducts
  publication-title: Acc. Chem. Res.
  contributor:
    fullname: Wang
– volume: 21
  start-page: 8935
  year: 2002
  end-page: 8948
  ident: bb0025
  article-title: Uracil in DNA--occurrence, consequences and repair
  publication-title: Oncogene
  contributor:
    fullname: Slupphaug
– volume: 15
  start-page: 1913
  year: 2016
  end-page: 1920
  ident: bb0175
  article-title: The functions of serine 687 phosphorylation of human DNA polymerase η in UV damage tolerance
  publication-title: Mol. Cell. Proteomics
  contributor:
    fullname: Wang
– volume: 66
  start-page: 788
  year: 2009
  end-page: 799
  ident: bb0195
  article-title: Participation of DNA repair in the response to 5-fluorouracil
  publication-title: Cell. Mol. Life Sci.
  contributor:
    fullname: Wilson
– volume: 22
  start-page: 4212
  year: 2021
  ident: bb0215
  article-title: Genomic uracil and aberrant profile of demethylation intermediates in epigenetics and hematologic malignancies
  publication-title: Int. J. Mol. Sci.
  contributor:
    fullname: Krokan
– volume: 25
  start-page: 750
  year: 1997
  end-page: 755
  ident: bb0105
  article-title: Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Krokan
– volume: 154
  start-page: 1380
  year: 2013
  end-page: 1389
  ident: bb0170
  article-title: Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
  publication-title: Cell
  contributor:
    fullname: Zhang
– volume: 47
  start-page: 980
  year: 2012
  end-page: 986
  ident: bb0265
  article-title: RNase H2-initiated ribonucleotide excision repair
  publication-title: Mol. Cell
  contributor:
    fullname: Burgers
– volume: 1168
  year: 2021
  ident: bb0155
  article-title: Chemical proteomic profiling of UTP-binding proteins in human cells
  publication-title: Anal. Chim. Acta
  contributor:
    fullname: Dai
– volume: 1168
  year: 2021
  ident: 10.1016/j.ijbiomac.2024.129951_bb0155
  article-title: Chemical proteomic profiling of UTP-binding proteins in human cells
  publication-title: Anal. Chim. Acta
  doi: 10.1016/j.aca.2021.338607
  contributor:
    fullname: Liu
– volume: 19
  start-page: 14
  year: 2014
  ident: 10.1016/j.ijbiomac.2024.129951_bb0095
  article-title: Base excision repair: a critical player in many games
  publication-title: DNA Repair (Amst)
  doi: 10.1016/j.dnarep.2014.03.030
  contributor:
    fullname: Wallace
– volume: 364
  start-page: 563
  issue: 1517
  year: 2009
  ident: 10.1016/j.ijbiomac.2024.129951_bb0100
  article-title: Uracil in DNA and its processing by different DNA glycosylases
  publication-title: Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci.
  doi: 10.1098/rstb.2008.0186
  contributor:
    fullname: Visnes
– volume: 41
  start-page: 5298
  issue: 49
  year: 2022
  ident: 10.1016/j.ijbiomac.2024.129951_bb0135
  article-title: The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer
  publication-title: Oncogene
  doi: 10.1038/s41388-022-02495-4
  contributor:
    fullname: Hu
– volume: 137
  year: 2021
  ident: 10.1016/j.ijbiomac.2024.129951_bb0240
  article-title: 5-fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: implication of DNA repair inhibition
  publication-title: Biomed. Pharmacother.
  doi: 10.1016/j.biopha.2021.111285
  contributor:
    fullname: Sethy
– volume: 22
  start-page: 1339
  issue: 4
  year: 2023
  ident: 10.1016/j.ijbiomac.2024.129951_bb0165
  article-title: Human mitochondrial protein HSPD1 binds to and regulates the repair of deoxyinosine in DNA
  publication-title: J. Proteome Res.
  doi: 10.1021/acs.jproteome.2c00854
  contributor:
    fullname: Zheng
– volume: 39
  start-page: 411
  issue: 7–9
  year: 2023
  ident: 10.1016/j.ijbiomac.2024.129951_bb0150
  article-title: AUF1 recognizes 8-oxo-guanosine embedded in DNA and stimulates APE1 endoribonuclease activity
  publication-title: Antioxid. Redox Signal.
  doi: 10.1089/ars.2022.0105
  contributor:
    fullname: Malfatti
– volume: 23
  start-page: 96
  issue: 1
  year: 2021
  ident: 10.1016/j.ijbiomac.2024.129951_bb0140
  article-title: AU-rich element RNA binding proteins: at the crossroads of post-transcriptional regulation and genome integrity
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms23010096
  contributor:
    fullname: Sidali
– volume: 32
  start-page: 3479
  issue: 11
  year: 2021
  ident: 10.1016/j.ijbiomac.2024.129951_bb0160
  article-title: Comprehensive profiling of CTP-binding proteins using a biotinylated CTP affinity probe
  publication-title: Chin. Chem. Lett.
  doi: 10.1016/j.cclet.2021.05.057
  contributor:
    fullname: Pan
– volume: 186
  start-page: 2425
  issue: 11
  year: 2023
  ident: 10.1016/j.ijbiomac.2024.129951_bb0260
  article-title: RNA polymerase drives ribonucleotide excision DNA repair in E. Coli
  publication-title: Cell
  doi: 10.1016/j.cell.2023.04.029
  contributor:
    fullname: Hao
– volume: 5
  start-page: 549
  issue: 4
  year: 2014
  ident: 10.1016/j.ijbiomac.2024.129951_bb0115
  article-title: Physiological networks and disease functions of RNA-binding protein AUF1
  publication-title: Wiley Interdiscip. Rev. RNA
  doi: 10.1002/wrna.1230
  contributor:
    fullname: Moore
– volume: 36
  start-page: 705
  issue: 3
  year: 2008
  ident: 10.1016/j.ijbiomac.2024.129951_bb0055
  article-title: Uracil recognition by replicative DNA polymerases is limited to the archaea, not occurring with bacteria and eukarya
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkm1023
  contributor:
    fullname: Wardle
– volume: 33
  start-page: 2077
  issue: 4
  year: 2022
  ident: 10.1016/j.ijbiomac.2024.129951_bb0180
  article-title: Next-generation sequencing-based analysis of the effect of N6-methyldeoxyadenosine modification on DNA replication in human cells
  publication-title: Chin. Chem. Lett.
  doi: 10.1016/j.cclet.2021.08.066
  contributor:
    fullname: Wang
– volume: 12
  start-page: 699
  issue: 9
  year: 2013
  ident: 10.1016/j.ijbiomac.2024.129951_bb0015
  article-title: A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported
  publication-title: DNA Repair (Amst)
  doi: 10.1016/j.dnarep.2013.05.002
  contributor:
    fullname: Galashevskaya
– volume: 76
  start-page: 1
  year: 2007
  ident: 10.1016/j.ijbiomac.2024.129951_bb0035
  article-title: Molecular mechanisms of antibody somatic hypermutation
  publication-title: Annu. Rev. Biochem.
  doi: 10.1146/annurev.biochem.76.061705.090740
  contributor:
    fullname: Di Noia
– volume: 41
  start-page: 8093
  issue: 25
  year: 2002
  ident: 10.1016/j.ijbiomac.2024.129951_bb0075
  article-title: Endogenous DNA lesions can inhibit the binding of the AP-1 (c-Jun) transcription factor
  publication-title: Biochemistry-Us
  doi: 10.1021/bi012180a
  contributor:
    fullname: Rogstad
– volume: 7
  start-page: 973
  issue: 6
  year: 2021
  ident: 10.1016/j.ijbiomac.2024.129951_bb0070
  article-title: Base-resolution analysis of deoxyuridine at the genome scale based on the artificial incorporation modified nucleobase
  publication-title: ACS Cent. Sci.
  doi: 10.1021/acscentsci.0c01504
  contributor:
    fullname: Wang
– volume: 47
  start-page: 4153
  issue: 8
  year: 2019
  ident: 10.1016/j.ijbiomac.2024.129951_bb0080
  article-title: Deoxyuridine in DNA has an inhibitory and promutagenic effect on RNA transcription by diverse RNA polymerases
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Cui
– volume: 17
  start-page: 2315
  issue: 8
  year: 2022
  ident: 10.1016/j.ijbiomac.2024.129951_bb0185
  article-title: Next-generation sequencing-based analysis of the roles of DNA polymerases v and θ in the replicative bypass of 8-oxo-7,8-dihydroguanine in human cells
  publication-title: ACS Chem. Biol.
  doi: 10.1021/acschembio.2c00415
  contributor:
    fullname: Liu
– volume: 14
  start-page: 680
  issue: 7
  year: 2018
  ident: 10.1016/j.ijbiomac.2024.129951_bb0065
  article-title: Genome-wide mapping reveals that deoxyuridine is enriched in the human centromeric DNA
  publication-title: Nat. Chem. Biol.
  doi: 10.1038/s41589-018-0065-9
  contributor:
    fullname: Shu
– volume: 9
  start-page: 94
  year: 2008
  ident: 10.1016/j.ijbiomac.2024.129951_bb0110
  article-title: High-fidelity correction of genomic uracil by human mismatch repair activities
  publication-title: BMC Mol. Biol.
  doi: 10.1186/1471-2199-9-94
  contributor:
    fullname: Larson
– volume: 47
  start-page: 4068
  issue: 8
  year: 2019
  ident: 10.1016/j.ijbiomac.2024.129951_bb0145
  article-title: Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkz076
  contributor:
    fullname: Alfano
– volume: 21
  start-page: 8935
  issue: 58
  year: 2002
  ident: 10.1016/j.ijbiomac.2024.129951_bb0025
  article-title: Uracil in DNA--occurrence, consequences and repair
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1205996
  contributor:
    fullname: Krokan
– volume: 384
  start-page: 87
  issue: 6604
  year: 1996
  ident: 10.1016/j.ijbiomac.2024.129951_bb0255
  article-title: A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA
  publication-title: Nature
  doi: 10.1038/384087a0
  contributor:
    fullname: Slupphaug
– volume: 25
  start-page: 750
  issue: 4
  year: 1997
  ident: 10.1016/j.ijbiomac.2024.129951_bb0105
  article-title: Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/25.4.750
  contributor:
    fullname: Nilsen
– volume: 22
  start-page: 4212
  issue: 8
  year: 2021
  ident: 10.1016/j.ijbiomac.2024.129951_bb0215
  article-title: Genomic uracil and aberrant profile of demethylation intermediates in epigenetics and hematologic malignancies
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms22084212
  contributor:
    fullname: Olinski
– volume: 96
  start-page: 9045
  issue: 16
  year: 1999
  ident: 10.1016/j.ijbiomac.2024.129951_bb0085
  article-title: A read-ahead function in archaeal DNA polymerases detects promutagenic template-strand uracil
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.96.16.9045
  contributor:
    fullname: Greagg
– volume: 21
  start-page: 1706
  issue: 5
  year: 2020
  ident: 10.1016/j.ijbiomac.2024.129951_bb0245
  article-title: One, no one, and one hundred thousand: the many forms of ribonucleotides in DNA
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms21051706
  contributor:
    fullname: Nava
– volume: 21
  start-page: 1522
  issue: 10
  year: 2014
  ident: 10.1016/j.ijbiomac.2024.129951_bb0200
  article-title: p53-directed translational control can shape and expand the universe of p53 target genes
  publication-title: Cell Death Differ.
  doi: 10.1038/cdd.2014.79
  contributor:
    fullname: Zaccara
– volume: 5
  start-page: 1407
  issue: 12
  year: 2006
  ident: 10.1016/j.ijbiomac.2024.129951_bb0010
  article-title: Quantitative determination of uracil residues in Escherichia coli DNA: contribution of ung, dug, and dut genes to uracil avoidance
  publication-title: DNA Repair (Amst)
  doi: 10.1016/j.dnarep.2006.06.009
  contributor:
    fullname: Lari
– volume: 110
  start-page: 3695
  issue: 39
  year: 2013
  ident: 10.1016/j.ijbiomac.2024.129951_bb0220
  article-title: Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1305624110
  contributor:
    fullname: Prorok
– volume: 26
  start-page: 261
  year: 2008
  ident: 10.1016/j.ijbiomac.2024.129951_bb0030
  article-title: Mechanism and regulation of class switch recombination
  publication-title: Annu. Rev. Immunol.
  doi: 10.1146/annurev.immunol.26.021607.090248
  contributor:
    fullname: Stavnezer
– volume: 66
  start-page: 1073
  issue: 6
  year: 2020
  ident: 10.1016/j.ijbiomac.2024.129951_bb0275
  article-title: RNases H1 and H2: guardians of the stability of the nuclear genome when supply of dNTPs is limiting for DNA synthesis
  publication-title: Curr. Genet.
  doi: 10.1007/s00294-020-01086-8
  contributor:
    fullname: Cerritelli
– volume: 77
  start-page: 36
  year: 2019
  ident: 10.1016/j.ijbiomac.2024.129951_bb0060
  article-title: Deoxyuracil in DNA and disease: genomic signal or managed situation?
  publication-title: DNA Repair (Amst)
  doi: 10.1016/j.dnarep.2019.02.014
  contributor:
    fullname: Chon
– volume: 20
  start-page: 201
  year: 1986
  ident: 10.1016/j.ijbiomac.2024.129951_bb0210
  article-title: Mutagenesis by apurinic/apyrimidinic sites
  publication-title: Annu. Rev. Genet.
  doi: 10.1146/annurev.ge.20.120186.001221
  contributor:
    fullname: Loeb
– volume: 15
  start-page: 1913
  issue: 6
  year: 2016
  ident: 10.1016/j.ijbiomac.2024.129951_bb0175
  article-title: The functions of serine 687 phosphorylation of human DNA polymerase η in UV damage tolerance
  publication-title: Mol. Cell. Proteomics
  doi: 10.1074/mcp.M115.052167
  contributor:
    fullname: Dai
– volume: 49
  start-page: 205
  issue: 2
  year: 2016
  ident: 10.1016/j.ijbiomac.2024.129951_bb0225
  article-title: Mass spectrometry-based quantitative strategies for assessing the biological consequences and repair of DNA adducts
  publication-title: Acc. Chem. Res.
  doi: 10.1021/acs.accounts.5b00437
  contributor:
    fullname: You
– volume: 16
  start-page: 3194
  issue: 14
  year: 1977
  ident: 10.1016/j.ijbiomac.2024.129951_bb0250
  article-title: Partial purification and characterization of a uracil DNA N-glycosidase from Bacillus subtilis
  publication-title: Biochemistry
  doi: 10.1021/bi00633a024
  contributor:
    fullname: Cone
– volume: 116
  start-page: 12688
  issue: 20
  year: 2016
  ident: 10.1016/j.ijbiomac.2024.129951_bb0045
  article-title: Functions and malfunctions of mammalian DNA-cytosine deaminases
  publication-title: Chem. Rev.
  doi: 10.1021/acs.chemrev.6b00296
  contributor:
    fullname: Siriwardena
– volume: 154
  start-page: 1380
  issue: 6
  year: 2013
  ident: 10.1016/j.ijbiomac.2024.129951_bb0170
  article-title: Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
  publication-title: Cell
  doi: 10.1016/j.cell.2013.08.021
  contributor:
    fullname: Ran
– volume: 12
  start-page: 153
  issue: 2
  year: 2021
  ident: 10.1016/j.ijbiomac.2024.129951_bb0130
  article-title: HNRNPD interacts with ZHX2 regulating the vasculogenic mimicry formation of glioma cells via linc00707/miR-651-3p/SP2 axis
  publication-title: Cell Death Dis.
  doi: 10.1038/s41419-021-03432-1
  contributor:
    fullname: Yu
– volume: 47
  start-page: 980
  issue: 6
  year: 2012
  ident: 10.1016/j.ijbiomac.2024.129951_bb0265
  article-title: RNase H2-initiated ribonucleotide excision repair
  publication-title: Mol. Cell
  doi: 10.1016/j.molcel.2012.06.035
  contributor:
    fullname: Sparks
– volume: 41
  start-page: 4207
  issue: 7
  year: 2013
  ident: 10.1016/j.ijbiomac.2024.129951_bb0090
  article-title: Novel inhibition of archaeal family-D DNA polymerase by uracil
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkt083
  contributor:
    fullname: Richardson
– volume: 16
  start-page: 5645
  issue: 12
  year: 1988
  ident: 10.1016/j.ijbiomac.2024.129951_bb0050
  article-title: Purification and characterization of porcine liver DNA polymerase γ: utilization of dUTP and dTTP during in vitro DNA synthesis
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/16.12.5645
  contributor:
    fullname: Mosbaugh
– volume: 45
  start-page: 977
  issue: 9
  year: 2013
  ident: 10.1016/j.ijbiomac.2024.129951_bb0040
  article-title: Evidence for APOBEC3B mutagenesis in multiple human cancers
  publication-title: Nat. Genet.
  doi: 10.1038/ng.2701
  contributor:
    fullname: Burns
– volume: 66
  start-page: 788
  issue: 5
  year: 2009
  ident: 10.1016/j.ijbiomac.2024.129951_bb0195
  article-title: Participation of DNA repair in the response to 5-fluorouracil
  publication-title: Cell. Mol. Life Sci.
  doi: 10.1007/s00018-008-8557-5
  contributor:
    fullname: Wyatt
– volume: 3
  start-page: 330
  issue: 5
  year: 2003
  ident: 10.1016/j.ijbiomac.2024.129951_bb0235
  article-title: 5-fluorouracil: mechanisms of action and clinical strategies
  publication-title: Nat. Rev. Cancer
  doi: 10.1038/nrc1074
  contributor:
    fullname: Longley
– volume: 10
  start-page: 1247
  issue: 5
  year: 2002
  ident: 10.1016/j.ijbiomac.2024.129951_bb0020
  article-title: RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(02)00742-6
  contributor:
    fullname: Harris
– volume: 1
  start-page: 376
  issue: 5
  year: 2002
  ident: 10.1016/j.ijbiomac.2024.129951_bb0190
  article-title: Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
  publication-title: Mol. Cell. Proteomics
  doi: 10.1074/mcp.M200025-MCP200
  contributor:
    fullname: Ong
– volume: 11
  start-page: 5321
  issue: 1
  year: 2020
  ident: 10.1016/j.ijbiomac.2024.129951_bb0205
  article-title: 5-FU promotes stemness of colorectal cancer via p53-mediated WNT/beta-catenin pathway activation
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-020-19173-2
  contributor:
    fullname: Cho
– volume: 79
  start-page: 109
  year: 2015
  ident: 10.1016/j.ijbiomac.2024.129951_bb0125
  article-title: Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells
  publication-title: Free Radical Bio. Med.
  doi: 10.1016/j.freeradbiomed.2014.11.018
  contributor:
    fullname: Ishii
– volume: 168
  start-page: 644
  issue: 4
  year: 2017
  ident: 10.1016/j.ijbiomac.2024.129951_bb0005
  article-title: Endogenous DNA damage as a source of genomic instability in cancer
  publication-title: Cell
  doi: 10.1016/j.cell.2017.01.002
  contributor:
    fullname: Tubbs
– volume: 29
  start-page: 2890
  issue: 9
  year: 2019
  ident: 10.1016/j.ijbiomac.2024.129951_bb0270
  article-title: RNase H1 and H2 are differentially regulated to process RNA-DNA hybrids
  publication-title: Cell Rep.
  doi: 10.1016/j.celrep.2019.10.108
  contributor:
    fullname: Lockhart
– volume: 403
  start-page: 220
  issue: 2
  year: 2010
  ident: 10.1016/j.ijbiomac.2024.129951_bb0120
  article-title: Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress
  publication-title: Biochem. Bioph. Res. Co.
  doi: 10.1016/j.bbrc.2010.11.011
  contributor:
    fullname: Hayakawa
– volume: 24
  start-page: 16903
  issue: 23
  year: 2023
  ident: 10.1016/j.ijbiomac.2024.129951_bb0230
  article-title: Cellular responses to widespread DNA replication stress
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms242316903
  contributor:
    fullname: Nickoloff
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Snippet Deoxyribouridine (dU) is an abnormal nucleoside in DNA and plays vital roles in multiple biological and physiological processes. Here, we conducted a mass...
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SubjectTerms DNA damage
DNA repair
Proteomics
Title Human RNA-binding protein HNRNPD interacts with and regulates the repair of deoxyribouridine in DNA
URI https://dx.doi.org/10.1016/j.ijbiomac.2024.129951
https://www.ncbi.nlm.nih.gov/pubmed/38325695
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Volume 262
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