Recent developments in ureteral stent: Substrate material, coating polymer and technology, therapeutic function

The ureteral stent is an effective treatment for clinical ureteral stricture following urological surgery, and the functional coating of the stent could effectively inhibit bacterial colonization and other complications. The present review provides an analysis and description of the materials used i...

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Published inColloids and surfaces, B, Biointerfaces Vol. 238; p. 113916
Main Authors Wen, Kai-chao, Li, Zheng-an, Liu, Ji-heng, Zhang, Chuan, Zhang, Feng, Li, Feng-qian
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.06.2024
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Summary:The ureteral stent is an effective treatment for clinical ureteral stricture following urological surgery, and the functional coating of the stent could effectively inhibit bacterial colonization and other complications. The present review provides an analysis and description of the materials used in ureteral stents and their coatings. Emphasis is placed on the technological advancements of functional coatings, taking into consideration the characteristics of these materials and the properties of their active substances. Furthermore, recent advances in enhancing the therapeutic efficacy of functional coatings are also reviewed. It is anticipated that this article will serve as a valuable reference providing insights for future research development on new drug-loaded ureteral stents. [Display omitted] •Function and clinical treatment significance of ureteral stent and its coating were provided.•Structural stability and interface suitability of different ureteral stents were described.•The structural characteristics and practical applications of ureteral stent coating drug carriers were overviewed.•Process technology and application for preparing ureteral stent coatings were analyzed.•Therapeutic effects and future development of ureteral coating stents are summarized and prospected.
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ISSN:0927-7765
1873-4367
DOI:10.1016/j.colsurfb.2024.113916