Distinguish on the viability of human umbilical cord mesenchymal stem cells using delayed luminescence

In this paper, we report the discrimination of the viability of human umbilical cord mesenchymal~ stem cells （hUC-MSCs） with photo-induced delayed luminescence （DL）. We measure the DL decay kinetics of hUC-MSCs using an ultraweak luminescence detection system, and find the significant difference in...

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Bibliographic Details
Published inOptoelectronics letters Vol. 10; no. 5; pp. 391 - 394
Main Author 陈平 李星 王岩 白华 林列
Format Journal Article
LanguageEnglish
Published Heidelberg Tianjin University of Technology 01.09.2014
Subjects
Lasers
Optical Devices
Optics
Photonics
Physics
Physics and Astronomy
动力学参数
延迟发光
检测系统
脐带
衰减速度
超微弱发光
重量分布
间充质干细胞
High Viability
Decay Rate Constant
Peak Weight
Umbilical Cord Mesenchymal Stem Cell
Stem Cell Review
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Summary:In this paper, we report the discrimination of the viability of human umbilical cord mesenchymal~ stem cells （hUC-MSCs） with photo-induced delayed luminescence （DL）. We measure the DL decay kinetics of hUC-MSCs using an ultraweak luminescence detection system, and find the significant difference in the weight distributions of the decay rate for hUC-MSCs with high and low viabilities. Spectral discrimination of hUC-MSCs with high and low viabilities is thus carried out by comparing the DL kinetics parameters, including the initial intensity, the peak decay rate and the peak weight value. Our results show that the novel optical method for the viability diagnosis of hUC-MSCs has a promising prospect.
Bibliography:In this paper, we report the discrimination of the viability of human umbilical cord mesenchymal~ stem cells （hUC-MSCs） with photo-induced delayed luminescence （DL）. We measure the DL decay kinetics of hUC-MSCs using an ultraweak luminescence detection system, and find the significant difference in the weight distributions of the decay rate for hUC-MSCs with high and low viabilities. Spectral discrimination of hUC-MSCs with high and low viabilities is thus carried out by comparing the DL kinetics parameters, including the initial intensity, the peak decay rate and the peak weight value. Our results show that the novel optical method for the viability diagnosis of hUC-MSCs has a promising prospect.
CHEN Ping, LI Xing , WANG Yan, BAI Hua , and LIN Lie （ 1. Key Laboratory of Optical Information Science Technology, Ministry of Education of China, Institute of Modern Optics, Nankai University, Tianjin 300071, China 2. School of Electronics and Information Engineering, Tianjin Polytechnic University, Tianjin 300387, China）
12-1370/TN
ISSN:1673-1905
1993-5013
DOI:10.1007/s11801-014-4099-2