Protective effects of Resveratrol in an experimental model of abdominal aortic aneurysm induction
Resveratrol (Rsv) is a natural antioxidant polyphenol with vasoprotective properties. We evaluated whether Rsv affects the inflammatory response in an experimental model of elastase-induced abdominal aortic aneurysm. Thirty male rats were subjected to aneurysm induction and treated or not with Rsv....
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Published in | Journal of Biological Research Vol. 84; no. 1; p. 122 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English Italian |
Published |
Pavia
PAGEPress Publications
01.01.2011
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Subjects | |
Online Access | Get full text |
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Summary: | Resveratrol (Rsv) is a natural antioxidant polyphenol with vasoprotective properties. We evaluated whether Rsv affects the inflammatory response in an experimental model of elastase-induced abdominal aortic aneurysm. Thirty male rats were subjected to aneurysm induction and treated or not with Rsv. Circulating levels of CD62L-monocyte subset, monocyte CD I 43 surface expression, MMP-9 plasma activity and TNFα serum levels were lower in Rsv-treated rats. In conclusion. Rsv acts as an anti-inflammatory compound and could be of great revelance to improve the immune response in AAA patients. |
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ISSN: | 1826-8838 2284-0230 |
DOI: | 10.4081/jbr.2011.4638 |