Disseminated epidermolytic acanthoma with disseminated superficial porokeratosis and verruca vulgaris in an immunosuppressed patient

A 40-year-old man who had received long term immunosuppressive treatment for 14 years following kidney transplantation developed multiple skin lesions on both antecubital fossae, scalp, and both lower extremities. Histopathologic findings from three skin regions revealed characteristic features of e...

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Bibliographic Details
Published inJournal of dermatology Vol. 22; no. 9; p. 690
Main Authors Chun, S I, Lee, J S, Kim, N S, Park, K D
Format Journal Article
LanguageEnglish
Published England 01.09.1995
Subjects
Adult
Epidermis - pathology
Humans
Hyperkeratosis, Epidermolytic - complications
Hyperkeratosis, Epidermolytic - immunology
Hyperkeratosis, Epidermolytic - pathology
Hyperplasia
Immunocompromised Host
Kidney Transplantation - immunology
Male
Porokeratosis - complications
Porokeratosis - immunology
Porokeratosis - pathology
Skin Diseases - complications
Skin Diseases - immunology
Skin Diseases - pathology
Warts - complications
Warts - immunology
Warts - pathology
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Summary:A 40-year-old man who had received long term immunosuppressive treatment for 14 years following kidney transplantation developed multiple skin lesions on both antecubital fossae, scalp, and both lower extremities. Histopathologic findings from three skin regions revealed characteristic features of epidermolytic hyperkeratosis, verruca vulgaris, and disseminated superficial porokeratosis, respectively. Although immunocompromised individuals may demonstrate verruca vulgaris or porokeratosis, disseminated epidermolytic acanthoma (DEA) has not been reported to be associated with immunosuppressed status. We suggest that immunosuppression may play a role in the pathogenesis of DEA, as shown in our case.
ISSN:0385-2407
DOI:10.1111/j.1346-8138.1995.tb03900.x