Histiocytic medullary reticulosis

The clinical and pathological features of histiocytic medullary reticulosis (HMR) are described in five patients. Treatment by splenectomy and the MOPP routine resulted in a transient improvement in platelet and neutrophil counts and resolution of anaemia and apparent prolongation of survival in two...

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Bibliographic Details
Published inAustralian and New Zealand journal of medicine Vol. 5; no. 4; p. 347
Main Authors Sullivan, J R, Ungar, B, Hicks, J D, Hurley, T H
Format Journal Article
LanguageEnglish
Published Australia 01.08.1975
Subjects
Adult
Female
Humans
Lymphatic Diseases - diagnosis
Lymphatic Diseases - therapy
Male
Middle Aged
Phagocytosis
Pregnancy
Pregnancy Complications
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Summary:The clinical and pathological features of histiocytic medullary reticulosis (HMR) are described in five patients. Treatment by splenectomy and the MOPP routine resulted in a transient improvement in platelet and neutrophil counts and resolution of anaemia and apparent prolongation of survival in two of the five patients. The relationship of HMR to other histiocytic disorders is discussed. HMR is defined as a unique malignant histiocytosis in which malignant histiocytes engage in phagocytosis of eryrhrocytes, leucocytes and platelets.
ISSN:0004-8291
DOI:10.1111/j.1445-5994.1975.tb03270.x