Canine Distemper Virus in Domesticated Cats and Pigs

• Published in: Advances in enzymology and related subjects Vol. 35; no. 6; pp. 803 - 806
• Main Authors: Appel, M., Sheffy, B. E., Percy, D. H., Gaskin, J. M.
• Format: Journal Article
• Language: English
• Published: United States 01.01.1974
• Subjects: Administration, Intranasal; animal diseases; animal health; Animals; Animals, Newborn; Brain; Cat Diseases - etiology; Cat Diseases - immunology; Cat Diseases - pathology; Cats; Cells, Cultured; Distemper - immunology; Distemper - pathology; Distemper Virus, Canine - growth & development; Distemper Virus, Canine - immunology; Distemper Virus, Canine - pathogenicity; Dogs; Fluorescent Antibody Technique; Injections; Lung; Macrophages; Neutralization Tests; Swine; Swine Diseases - etiology; Swine Diseases - immunology; Swine Diseases - pathology; Thymus Gland - pathology

Twenty-two cats and 17 pigs, ranging in age from 2 days to 2 years, were found to be susceptible to intranasal inoculation of virulent canine distemper ( cd ) virus. Virus replicated in lymphatic tissues and in macrophages, but not in surface epithelium or brain. Infection with cd virus in cats and...