Synthesis and evaluation of a Zn-Al layered double hydroxide for the removal of ochratoxin A. Greenness assessment

• Published in: Analytical methods Vol. 14; no. 29; pp. 2841 - 2848
• Main Authors: Ponce, María del Valle, Cina, Mariel, López, Carlos, Cerutti, Soledad
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 29.07.2022
• Subjects: Aluminum; Chemical precipitation; Food; High performance liquid chromatography; Hydroxides; Liquid chromatography; Mass spectrometry; Mass spectroscopy; Mycotoxins; Nanomaterials; Ochratoxin A; Synthesis; Toxins; Zinc
• ISSN: 1759-9660; 1759-9679
• DOI: 10.1039/d2ay00819j

The retention behavior of a dangerous toxin, ochratoxin A (OTA), present in food samples and derivatives was evaluated using Layered Double Hydroxides (LDHs). This nanomaterial composed mostly of zinc and aluminum was synthesized by the co-precipitation method and the obtained solid was characterized by different techniques, such as XRD, FTIR, TGA, SEM, and N 2 adsorption-desorption isotherms. Experimental conditions were optimized by chemometric tools. Ochratoxin A determination was performed using an ultra-high-performance liquid chromatography (UHPLC) system coupled to tandem mass spectrometry. From the findings, quantitative removal of the mycotoxin was achieved. Thus, a novel, nanostructured, innocuous, low-cost, easily synthesized material, such as the Zn-Al layered double hydroxide, is proposed for ochratoxin A removal. This might represent an effective and sustainable approach with potential applications to different types of food and feed samples. The retention behavior of a dangerous toxin, ochratoxin A (OTA), present in food samples and derivatives was evaluated using Layered Double Hydroxides (LDHs).