Chemical composition and antimicrobial activity of the essential oil of Artemisia lavandulaefolia

• Published in: Planta medica Vol. 71; no. 6; pp. 575 - 577
• Main Authors: Cha, J.D, Jeong, M.R, Choi, H.J, Jeong, S.I, Moon, S.E, Yun, S.I, Kim, Y.H, Kil, B.S, Song, Y.H
• Format: Journal Article
• Language: English
• Published: Germany 01.06.2005
• Subjects: Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; antibacterial properties; Artemisia; Artemisia lavandulaefolia; chemical composition; essential oils; Gas Chromatography-Mass Spectrometry; Gram-Negative Bacteria - drug effects; Gram-Positive Bacteria - drug effects; Humans; medicinal plants; Microbial Sensitivity Tests; Phytotherapy; Plant Oils - chemistry; Plant Oils - pharmacology; South Korea
• ISSN: 0032-0943; 1439-0221
• DOI: 10.1055/s-2005-864164

The chemical components of the essential oil obtained from Artemisia lavandulaefolia DC. were analyzed by GC-MS. Ninety-nine compounds accounting for 94.9 % of the essential oil were identified. The major compounds in the essential oil were beta-caryophyllene (16.1 %), cis-chrysanthenol (7.0 %), 1,8-cineole (5.6 %), borneol (5.3 %), trans-beta-farnesene (5.1 %), camphor (4.9 %), yomogi alcohol (4.5 %), alpha-terpineol (3.9 %), and alpha-humulene oxide (3.3 %). The essential oil and some of its major compounds were tested for antimicrobial activity against 15 different genera of oral bacteria. The essential oil of A. lavandulaefolia exhibited considerable inhibitory effects against all obligate anaerobic bacteria (MIC values, 0.025 to 0.05 mg/mL; MBC values, 0.025 to 0.1 mg/mL) tested, while its major compounds demonstrated different degrees of growth inhibition.