Fused 18F-Choline PET/MRI: A potential non-invasive biomarker imaging tool in cerebral vasculitis

Primary CNS vasculitis is an inflammatory brain disease commonly misdiagnosed affecting the medium and small vessels of the CNS. Due to its broad and non-specific clinical and radiological manifestations; Its diagnosis remains challenging. New diagnostic tools and biomarkers which increase specifici...

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Bibliographic Details
Published inRadiology case reports Vol. 16; no. 12; pp. 3794 - 3797
Main Authors Abouzied, Moheieldin, AlSalloum, Riyadh, AlHarbi, Omar, Suhaibani, Mohanned Al, AlMuhaideb, Ahmad, Sugair, Abdulaziz Al, Qahtani, Mohammed Al
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.12.2021
Elsevier
Subjects
18F-choline PET/MRI
Biomarker imaging
Case Report
Cerebral vasculitis
Biomarker imaging
18F-choline PET/MRI
Cerebral vasculitis
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Summary:Primary CNS vasculitis is an inflammatory brain disease commonly misdiagnosed affecting the medium and small vessels of the CNS. Due to its broad and non-specific clinical and radiological manifestations; Its diagnosis remains challenging. New diagnostic tools and biomarkers which increase specificity and facilitate the diagnosis for patients with suspected vasculitis are highly desirable to enable physicians to start therapy that can alter its potential aggressive course like immunosuppressant. This case report highlights the potential role of 18F-choline PET/MRI as a novel imaging tool that might help in the right clinical scenario in the diagnosis of this disease. Furthermore, it speculates on its secondary role in monitoring the response to immunosuppressant therapy.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2021.09.017