Birth of rhesus monkey infant after transfer of embryos derived from in-vitro matured oocytes: Short communication

Although strategies for in-vitro maturation of oocytes from rodents and domestic species have been relatively successful, application of these techniques to primates has not met with similar success. Currently, evaluation of the developmental capacity of oocytes following fertilization is the only r...

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Bibliographic Details
Published inHuman reproduction (Oxford) Vol. 15; no. 11; pp. 2411 - 2414
Main Authors Schramm, R.Dee, Paprocki, Ann Marie
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.11.2000
Subjects
Animals
Animals, Newborn
Cells, Cultured
Cellular Senescence
Chorionic Gonadotropin - metabolism
Cricetinae
Embryo Transfer
Female
in-vitro fertilization
in-vitro maturation
Labor, Obstetric
Macaca mulatta - physiology
Male
oocyte
Oocytes - physiology
Pregnancy
rhesus monkey infant
Ultrasonography, Prenatal
oocyte
in-vitro fertilization
in-vitro maturation
embryo transfer
rhesus monkey infant
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Summary:Although strategies for in-vitro maturation of oocytes from rodents and domestic species have been relatively successful, application of these techniques to primates has not met with similar success. Currently, evaluation of the developmental capacity of oocytes following fertilization is the only reliable means to assess cytoplasmic maturation. Although rhesus monkey blastocysts have previously been produced from in-vitro matured oocytes, full developmental competence has not been demonstrated by term development. Here we report the birth of the first non-human primate infant derived from in-vitro matured oocytes.
Bibliography:ark:/67375/HXZ-PK3FBMBJ-0
PII:1460-2350
local:0152411
istex:81E1283CAC699C91EE903586ECA93B2C3E11F6EF
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0268-1161
1460-2350
1460-2350
DOI:10.1093/humrep/15.11.2411