The effect of ranitidine, cimetidine or famotidine on low‐dose post‐prandial alcohol absorption

• Published in: Alimentary pharmacology & therapeutics Vol. 5; no. 3; pp. 263 - 272
• Main Authors: FRASER, A. G., PREWETT, E. J., HUDSON, M., SAWYERR, A. M., ROSALKI, S. B., POUNDER, R. E.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.06.1991; Blackwell
• Subjects: Adult; Biological and medical sciences; Cimetidine - administration & dosage; Cimetidine - pharmacology; Digestive system; Double-Blind Method; Eating; Ethanol - blood; Ethanol - metabolism; Famotidine - administration & dosage; Famotidine - pharmacology; Humans; Intestinal Absorption - drug effects; Male; Medical sciences; Pharmacology. Drug treatments; Ranitidine - administration & dosage; Ranitidine - pharmacology; Human; Drug alcohol interaction; Absorption; Ethanol; H2 receptor; Alcoholemia; Antiulcer agent; Normal; Antihistaminic

SUMMARY Plasma alcohol concentration following oral ingestion of 0.3 g/kg of alcohol (ethyl alcohol), one hour after an evening meal, was measured in four groups of 12 healthy subjects. Each group had a control study and a repeat study after 7 days dosing with either placebo or an H2‐receptor antago...