Advances in high-resolution mass spectrometry techniques for analysis of high mass-to-charge ions

• Published in: Mass spectrometry reviews Vol. 42; no. 6; pp. e21790 - 2445
• Main Authors: Lai, Yin-Hung, Wang, Yi-Sheng
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.11.2023
• Subjects: Macromolecules; Mass spectroscopy; Proteomics; high-resolution mass spectrometry; quadrupole; top-down proteomics; time-of-flight; native MS; high mass-to-charge; Fourier-transform

A major challenge in modern mass spectrometry (MS) is achieving high mass resolving power and accuracy for precision analyses in high mass-to-charge (m/z) regions. To advance the capability of MS for increasingly demanding applications, understanding limitations of state-of-the-art techniques and th...