Blood flow during 2-Torr exposures at different decompression rates

Central and peripheral blood flow of denitrogenated dogs, measured in the femoral artery and aorta, declined rapidly and ceased within mean times of 28, 35, 70, or 90 s after 1-, 10-, 30-, or 60-s decompressions from 258 Torr to 2 Torr, respectively. Neither arterial nor venous hypoxemia was seen af...

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Bibliographic Details
Published inJournal of applied physiology (1948) Vol. 38; no. 4; p. 643
Main Authors Cooke, J P, Olson, R M
Format Journal Article
LanguageEnglish
Published United States 01.04.1975
Subjects
Animals
Aorta
Blood Circulation
Blood Pressure
Decompression
Dogs
Femoral Artery
Male
Oxygen - blood
Pressure
Time Factors
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Summary:Central and peripheral blood flow of denitrogenated dogs, measured in the femoral artery and aorta, declined rapidly and ceased within mean times of 28, 35, 70, or 90 s after 1-, 10-, 30-, or 60-s decompressions from 258 Torr to 2 Torr, respectively. Neither arterial nor venous hypoxemia was seen after 1-s decompressions since the hypoxic blood did not reach the aorta. In contrast, arterial and venous O2 saturation levels dropped as low as 12 or 6% following 10- to 60-s decompressions since circulation continued. A severe and transient decerebratelike rigidity and subsequent temporary flaccid paralysis of the hind legs was seen during recovery from decompressions slower than 1 s, whereas only a mild temporary flaccid paralysis was frequently present after 1-s decompression. The more severe responses following 10- to 60-s decompressions are associated with the greater hypoxemia after slow decompressions, indicating tissue hypoxia is more severe when decompression rate is slow.
ISSN:0021-8987
DOI:10.1152/jappl.1975.38.4.643