Half-and-half cells in lichen planus. A possible clue to the origin and early formation of colloid bodies

In the course of a study of wound healing in four patients with lichen planus, we found transformed keratinocytes with a hitherto undescribed ultrastructure in both wounded and undisturbed papules. We have called these epidermal cells half-and-half cells because they showed changes on the one hand o...

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Bibliographic Details
Published inBritish journal of dermatology (1951) Vol. 98; no. 4; p. 417
Main Authors Eady, R A, Cowen, T
Format Journal Article
LanguageEnglish
Published England 01.04.1978
Subjects
Colloids
Humans
Lichen Planus - pathology
Microscopy, Electron
Organoids
Skin - injuries
Skin - ultrastructure
Wound Healing
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Summary:In the course of a study of wound healing in four patients with lichen planus, we found transformed keratinocytes with a hitherto undescribed ultrastructure in both wounded and undisturbed papules. We have called these epidermal cells half-and-half cells because they showed changes on the one hand of increased synthetic activity and, on the other hand, of fibrillar transformation closely resembling that seen in fully developed colloid bodies. We suggest that these half-and-half cells may provide a useful clue to the early changes occurring in colloid body formation.
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1978.tb06535.x