Uncovering the underlying physical mechanisms of biological systems via quantification of landscape and flux

In this review, we explore the physical mechanisms of biological processes such as protein folding and recognition, ligand binding, and systems biology, including cell cycle, stem cell, cancer, evolution, ecology, and neural networks. Our approach is based on the landscape and flux theory for nonequ...

Full description

Saved in:
Bibliographic Details
Published inChinese physics B Vol. 25; no. 1; pp. 244 - 269
Main Author 徐丽 楚夏昆 晏致强 郑喜亮 张坤 张锋 闫晗 吴畏 汪劲
Format Journal Article
LanguageEnglish
Published 01.01.2016
Subjects
Biological
Biology
Dynamical systems
Dynamics
Flux
Landscapes
Neural networks
Stem cells
景观
物理机制
生物系统
系统生物学
细胞周期
蛋白质折叠
通量
量化
Online AccessGet full text
ISSN1674-1056
2058-3834
1741-4199
DOI10.1088/1674-1056/25/1/016401

Cover

More Information
Summary:In this review, we explore the physical mechanisms of biological processes such as protein folding and recognition, ligand binding, and systems biology, including cell cycle, stem cell, cancer, evolution, ecology, and neural networks. Our approach is based on the landscape and flux theory for nonequilibrium dynamical systems. This theory provides a unifying principle and foundation for investigating the underlying mechanisms and physical quantification of biological systems.
Bibliography:landscape, flux
In this review, we explore the physical mechanisms of biological processes such as protein folding and recognition, ligand binding, and systems biology, including cell cycle, stem cell, cancer, evolution, ecology, and neural networks. Our approach is based on the landscape and flux theory for nonequilibrium dynamical systems. This theory provides a unifying principle and foundation for investigating the underlying mechanisms and physical quantification of biological systems.
11-5639/O4
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1674-1056
2058-3834
1741-4199
DOI:10.1088/1674-1056/25/1/016401