Continuous EEG Monitoring in Critically Ill Children and Prognostic Factors for Short-term Outcome: An Observational Study

• Published in: The journal of pediatric research Vol. 9; no. 3; pp. 228 - 235
• Main Authors: Balci, Ozlem Ozdemir, Simsek, Erdem, Ozkaya, Pinar Yazici, Kanmaz, Seda, Dokurel, Ipek, Serin, Hepsen Mine, Yilmaz, Sanem, Aktan, Gul, Tekgul, Hasan, Karapinar, Bulent, Gokben, Sarenur
• Format: Journal Article
• Language: English
• Published: Galenos Yayinevi Tic. Ltd 01.09.2022; Galenos Yayinevi
• Subjects: acute encephalopathy; Care and treatment; children; continuous eeg monitoring; Electroencephalography; Encephalopathy; intensive care; Methods; Patient monitoring; Patient outcomes; Pediatric intensive care; Pediatric research; Prognosis; Turkey
• ISSN: 2147-9445; 2587-2478; 2147-9445
• DOI: 10.4274/jpr.galenos.2022.77885

Aim: To evaluate the association of etiology, continuous electroencephalography (cEEG) findings and neuroimaging findings with short-term outcomes for patients admitted to a pediatric intensive care unit (PICU) for acute encephalopathy. Materials and Methods: A total of 24 children admitted to a PICU for acute encephalopathy were enrolled into this study. The etiology, treatment, duration of stay in the PICU, their demographic information and their past medical history were recorded. cEEG was initiated as quickly as possible following admission to the PICU and continued for at least 24 hours. Their short-term prognosis was evaluated by the Pediatric Cerebral Performance Category score (PCPC) at PICU discharge. Results: The most common cause was traumatic brain injury comprising 25% (n=6) of all cases. Other common causes were asphyxia (hanging, foreign body aspiration, drowning) (n=4, 16.67%) and intoxication (n=3, 12.5%). Twenty-two patients underwent cranial imaging. The most common findings in CT were hemorrhage (n=6, 30%) and ischemia/edema (n=6, 30%). Fourteen patients had unfavorable PCPC outcome scores. There was a tendency for poorer outcomes in those patients with hemorrhage/fracture or ischemia/edema in the imaging and for those patients who needed either pre-hospital CPR or had non-convulsive seizures but without statistical significance. Conclusion: cEEG in critically ill children is useful for detecting both epileptic and non-epileptic events. The use of cEEG in PICUs can be helpful for the better management of cases. Keywords: Acute encephalopathy, children, continuous EEG monitoring, intensive care, prognosis