Cut-off Values of Diagnostic Indices to Detect Iron Deficiency in Chinese Breast-fed Infants

• Published in: Biomedical and environmental sciences Vol. 29; no. 11; pp. 829 - 833
• Main Authors: WU, Qin, REN, Jie, YANG, Li Chen, LIU, Jie, WEI, Jun, ZHANG, Wei, LI, Na, WANG, Yue Jiao, YAN, Li Huang, MA, Jian Rong, YANG, Xiao Guang
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.11.2016; Department of chronic disease control and Prevention, Tongzhou District Center for Disease Control and Prevention, Beijing 101100, China%The Key Laboratory of Trace Element Nutrition M0H, National Institute of Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China%The People's Hospital of Beijing University, Beijing 100044, China%Beijing Maternity Hospital Affiliated to Capital Medical University, Beijing 100026, China
• Subjects: Anemia, Iron-Deficiency - blood; Anemia, Iron-Deficiency - diagnosis; Breast Feeding; China; Humans; Infant; Reference Values; 中国; 婴儿; 检测; 母乳喂养; 缺铁性贫血; 营养缺乏症; 诊断; 转铁蛋白受体
• ISSN: 0895-3988; 2214-0190
• DOI: 10.3967/bes2016.111

Iron deficiency anemia is one of the most prevalent nutritional deficiency worldwide. The commonly used cut-off values for identifying iron deficiency are extrapolated from older children and may not be suitable for infants. Therefore, our study aimed to establish appropriate cut-off values for the evaluation of iron status in Chinese infants. Pregnant women who delivered at 〉37 gestational weeks with normal iron status were recruited. Later, infants with normal birth weight and who were breastfed in the first 4 months were selected. Blood samples were collected to assess hemoglobin, serum ferritin, soluble transferrin receptor, mean corpuscular volume and free erythrocyte protoporphyrin. Cut-offs of all iron indices were determined as the limit of 95% confidence interval.